Results 21 to 30 of about 7,287 (194)
IRAK‐M mediates Toll‐like receptor/IL‐1R‐induced NFκB activation and cytokine production [PDF]
EMBO Journal, 2013 Hao Zhou, Minjia Yu, Peng Yao
exaly +2 more sources
Interleukin-1 receptor-associated kinase 2- and protein kinase D1-dependent regulation of IRAK-monocyte expression by CpG DNA. [PDF]
PLoS ONE, 2012 As a part of the negative feedback mechanism, CpG DNA induces IRAK-M expression in monocytic cells. In the present study we investigated a biochemical signaling pathway and the transcription factors responsible for CpG DNA-mediated Irak-m gene expression.
Young-In Kim +4 more
doaj +1 more source
Innate Immunity, 2021 TLRs recognizing PAMPS play a role in local immunity and participate in implant-associated loosening. TLR-mediated signaling is primarily regulated by IL-1 receptor associated kinase-M (IRAK-M) negatively and IRAK-4 positively.
Yang-chun Zhang +3 more
doaj +1 more source
Interleukin Receptor Associated Kinase 1 Signaling and Its Association with Cardiovascular Diseases
Reviews in Cardiovascular Medicine, 2022 Toll-like receptors (TLRs) and interleukin-1 receptor (IL-1R) directly interact with intracellular interleukin receptor associated kinase (IRAK) family members to initialize innate immune and inflammatory responses following activation by pathogen ...
Youjing Zheng, Jia-Qiang He
doaj +1 more source
Heliyon, 2022 The IL-23/IL-17 axis plays an important role in the development of autoimmune diseases, but the mechanism regulating IL-23 production is mainly unknown.
Rui Yamaguchi +6 more
doaj +1 more source
Microorganisms, 2021 Staphylococcus aureus inhibits complement activity by secreting a variety of toxins. However, the underlying mechanism of complement component regulation by lipoteichoic acid (LTA), a cell wall component of S. aureus, has not been elucidated.
Bong Jun Jung +4 more
doaj +1 more source
¿Un califato islámico en el Sahel?
Comillas Journal of International Relations, 2020 Este artículo compara las condiciones políticas, sociales e históricas del Estado de Irak en el momento de la expansión territorial de Daesh con las condiciones políticas, sociales e históricas presentes actualmente en el Estado de Mali. Para el análisis
Iván Santo-Tomás López
doaj +1 more source
Frontiers in Medicine, 2021 Programs to prevent mother-to-child HIV transmission do not reduce the number of infants exposed during pregnancy and breastfeeding. HIV-exposed but uninfected children (HEU) present higher risk of morbidity and mortality than HIV-unexposed and ...
Marina Rubio-Garrido +8 more
doaj +1 more source
Frontiers in Immunology, 2014 Chronic inflammation has long been associated with the development of cancer. Amongst the various signaling pathways within cancer cells that can incite the expression of inflammatory molecules are those that activate IL-1 receptor associated kinases ...
Ajay eJain +2 more
doaj +1 more source
Brazilian Journal of Poultry Science, 2022 The aim of this study is to determine the serum amino acid profile using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS / MS) in healthy male and female geese of the same age that were raised in similar care and feeding conditions.
E Yavuz +5 more
doaj +1 more source