Results 31 to 40 of about 12,977 (200)

Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures

open access: yesCurrent Issues in Molecular Biology, 2022
Angiotensin IV (Ang IV), a metabolite of Angiotensin II, is a bioactive hexapeptide that inhibits the insulin-regulated aminopeptidase (IRAP). This transmembrane zinc metallopeptidase with many biological functions has in recent years emerged as a new ...
Frida Stam   +8 more
doaj   +1 more source

The diagnosis of immune-related pancreatitis disguised as multifocal lesions on MRI by endoscopic ultrasound-guided fine-needle biopsy: A case report

open access: yesFrontiers in Immunology, 2022
Immune checkpoint inhibitor (ICI)–related acute pancreatitis (irAP) is a rare, potentially life-threatening immune-related adverse event. Whereas CT and MRI remain first-line diagnostic imaging modalities, more patients are presenting with atypical irAP ...
Wen Shi   +6 more
doaj   +1 more source

Escenas de carreteras videojuegos para medir la percepción del peligro en conductores experimentados

open access: yesAvances, 2021
Los conductores experimentados desarrollan habilidades de percepción del peligro con la práctica de conducción. La percepción del peligro se puede determinar usando diversas metodologías tales como fotos, videos, simuladores o recorridos reales.
Yasmany García-Ramírez, Janina Tapia
doaj   +1 more source

Percepción del peligro del conductor novato en carreteras de montaña: un caso de estudio en Ecuador

open access: yesAvances, 2021
Los conductores novatos tienen una mayor probabilidad de tener un siniestro vial que los conductores experimentados. Detectar el peligro es una de las habilidades que este tipo de conductores deben adquirir con la edad y la experiencia. Con ello se puede
Yasmany Damián García Ramírez   +1 more
doaj   +1 more source

Identifying the Crash Worthiness and Crash Avoidance Factors Based on Road Features [PDF]

open access: yesE3S Web of Conferences, 2023
The increased rate of road fatalities ad injured has been a vital issue. Risk assessment of road projects is essential in the pre-construction stages to prevent road crashes from occurring in the operational stage. Identifying the contributing factors of
Shokat Doaa M., Jameel Abeer Khudhur
doaj   +1 more source

From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase

open access: yesFrontiers in Pharmacology, 2020
It was reported three decades ago that intracerebroventricular injection of angiotensin IV (Ang IV, Val-Tyr-Ile-His-Pro-Phe) improved memory and learning in the rat. There are several explanations for these positive effects of the hexapeptide and related
Mathias Hallberg, Mats Larhed
doaj   +1 more source

Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro‐Oxindole Dihydroquinazolinones as IRAP Inhibitors

open access: yesChemistryOpen, 2020
Insulin‐regulated aminopeptidase (IRAP) is a new potential macromolecular target for drugs aimed for treatment of cognitive disorders. Inhibition of IRAP by angiotensin IV (Ang IV) improves the memory and learning in rats.
Karin Engen   +10 more
doaj   +1 more source

Genetic Diversity of Wheat Genotypes based on Resistance to Powdery Mildew, Grain Yield, Yield Components and Molecular Markers [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2019
Objective Genetic diversity in field crops has important role in breeding programs. The object of this study were to evaluate the genetic diversity and association analysis of morphological traits and mildew disease of wheat germplasm.
somayeh saravani   +4 more
doaj   +1 more source

Comparative retrotransposon analysis of mutant and non-mutant rice varieties grown at different salt concentrations

open access: yesBiotechnology & Biotechnological Equipment, 2022
This study investigated the effects of retrotransposon movements on the regeneration of 15- and 30-day-old leaves and roots of four different rice varieties grown in tissue culture medium at different salt concentrations (0, 50, 100, and 200 mmol/L) by ...
Yunus Emre Arvas   +3 more
doaj   +1 more source

Multiparametric vs. Inferior Vena Cava–Based Estimation of Right Atrial Pressure

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Right atrial pressure (RAP) can be estimated by echocardiography from inferior vena cava diameter and collapsibility (eRAPIVC), tricuspid E/e′ ratio (eRAPE/e′), or hepatic vein flow (eRAPHV).
Matteo Toma   +14 more
doaj   +1 more source

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