Results 161 to 170 of about 24,207 (226)

SOCS2 Downregulation Is Associated with a Ferro-Aging-Related Transcriptomic Signature in Proximal Tubular Cells in Chronic Kidney Disease. [PDF]

Biomedicines
Xia B, Zhou R, Chen J, Li G.
europepmc   +1 more source

Irf3 and Irf7 induce epigenetic changes to promote pancreatic carcinogenesis

The interferon regulatory factors 3 and 7 (Irf3, Irf7) are transcription factors downstream of the TLR3 pathway. We discovered an overexpression of Tlr3, Irf3 and Irf7 in pancreatic acinar-to-ductal metaplasia (ADM) and tumor cells.
Schreiner, Nicole, Beyer, Georg, Kleeff, Jörg, Steiger, Katja, Straub, Tobias, Hamidach, Hannah, Imhof, Axel, Mayerle, Julia, Mahajan, Ujjwal M, Regel, Ivonne, Benitz, Simone, Schotta, Gunnar, Fahr, Lisa, Mutter, Jurik, Michalski, Christoph W, Terrasi, Andrea, Lauber, Kirsten   +16 more
core  

TLR7 signaling aggravates lung inflammation associated with increased anti-Scl-70 autoantibody production in murine bleomycin-induced systemic sclerosis. [PDF]

Front Immunol
Evangelista JF, Nisperuza Vidal AK, Xu D, Islamuddin M, Chen Y, Wang C, Freitas R, Liu S, Engler-Chiurazzi E, Blair RV, Datta PK, Qin X.   +11 more
europepmc   +1 more source

An interferonopathy associated with a monoallelic variant in TRIM28. [PDF]

Pediatr Rheumatol Online J
Gomes SM, Omoyinmi E, Hong Y, Rice G, Seabra L, Bondet V, Duffy D, Anderson G, Adams F, McMorrow F, Papadopoulou C, Gomes JAM, Brogan P.   +12 more
europepmc   +1 more source

The 3' UTR Pseudoknot-Containing Region of Arteriviruses Acts as a PAMP to Activate RIG-I- and TLR8-Dependent Type I Interferon Responses. [PDF]

Viruses
Xie S, Zhang L, Sun YG, Shu M.
europepmc   +1 more source

Kaiso overexpression promotes an interferon immune response in murine intestines. [PDF]

BMC Genomics
Lessey LR, Adan H, Robinson SC, Chaudhary R, Sivakumar S, Ali Fairbairn S, Mohammadi D, Kim K, Alleyne D, Houlahan KE, Bédard PA, Cowan RW, Daniel JM.   +12 more
europepmc   +1 more source

N-Myc and STAT interactor as a context-dependent switch in innate antiviral immunity. [PDF]

Front Immunol
Han L, Xu X, Zhao F, Mao L, Guo Y, Gao M.   +5 more
europepmc   +1 more source

Neutrophil-microglia communication through the C3-C3aR1 axis contributes to secondary neuroinflammation after traumatic brain injury. [PDF]

Front Immunol
Ma T, Zhang Y, Wang X, Ren X, Jiao L, Pang K, Liu C, Zhou Z, Zhao P, Zhang H, Fu Y, Li L, Li Y, Zhao Z.   +13 more
europepmc   +1 more source

Alpha-herpesvirus UL55 synergizes with ICP27 to suppress type I interferon production through conserved and host-adapted mechanisms. [PDF]

J Virol
Wu Y, Zhang M, Sun A, Yang Q, An R, Wang M, Chen S, Jia R, Liu M, Yang Q, Tian B, Ou X, Huang J, Sun D, Zhu D, Zhao X, Zhang S, He Y, Wu Z, Cheng A.   +19 more
europepmc   +1 more source

Overweight and obesity induce Toll-like receptor 2-induced Type I IFN signaling. [PDF]

NPJ Metab Health Dis
Elkins M, Al-Musa A, Chiñas M, Woods B, Bourdine A, Ludwig-Radtke L, LaBere B, Habiballah S, Nguyen AA, Ohsumi TK, Gutierrez-Arcelus M, Fleischman A, Taudte V, Chou J.   +13 more
europepmc   +1 more source