Results 151 to 160 of about 24,207 (226)

Function of IRF3 and IRF7 in the MCMV infection model

open access: yes, 2009
IRF3 und IRF7 sind die zentralen Transkriptionsfaktoren zur Induktion von Typ I IFN bei einer Virusinfektion. In der vorliegenden Dissertation wurde die Rolle von IRF3 und IRF7 bei der systemischen Infektion mit murinem Zytomegalievirus (MCMV) im ...
Steinberg, Christian
core  

The CD97-PPM1G axis dampens antiviral immunity by dephosphorylating IRF7 in type I interferon pathway.

open access: yes
The activation of type I interferon (IFN-I) signaling is crucial for defending host cells against viral infections. A comprehensive IFN-I response necessitates the activation of several cellular factors, among them Interferon Regulator Factor 7 (IRF7 ...
Wang, Hongmei   +17 more
core   +1 more source

A highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-α, enhancing antiviral defense and exacerbating autoimmunity. [PDF]

open access: yesAm J Hum Genet
Virolainen SJ   +64 more
europepmc   +1 more source

Bacterial stimulation triggers IRF7-mediated IFN-λ production in hepatocytes to attenuate sepsis. [PDF]

open access: yesCell Mol Life Sci
Ma W   +8 more
europepmc   +1 more source

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