Function of IRF3 and IRF7 in the MCMV infection model
IRF3 und IRF7 sind die zentralen Transkriptionsfaktoren zur Induktion von Typ I IFN bei einer Virusinfektion. In der vorliegenden Dissertation wurde die Rolle von IRF3 und IRF7 bei der systemischen Infektion mit murinem Zytomegalievirus (MCMV) im ...
Steinberg, Christian
core
The activation of type I interferon (IFN-I) signaling is crucial for defending host cells against viral infections. A comprehensive IFN-I response necessitates the activation of several cellular factors, among them Interferon Regulator Factor 7 (IRF7 ...
Wang, Hongmei +17 more
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A highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-α, enhancing antiviral defense and exacerbating autoimmunity. [PDF]
Virolainen SJ +64 more
europepmc +1 more source
Bacterial stimulation triggers IRF7-mediated IFN-λ production in hepatocytes to attenuate sepsis. [PDF]
Ma W +8 more
europepmc +1 more source
Interferon Regulatory Factors as Potential Therapeutic Targets in Cardiovascular Disease: Focusing on Vascular Inflammation. [PDF]
Bai C, Liu W, Wang Y, Zhu H, Fan X.
europepmc +1 more source
HMGN5 promotes renal tubular inflammation and pyroptosis‑associated signaling in chronic kidney disease via the IFNAR2 axis. [PDF]
Rong X +6 more
europepmc +1 more source
IRF7 expression associated with low risk of bone metastasis
openaire +3 more sources
Publisher Correction: IRF7 links HK1-dependent histone lactylation to fibroblast activation and cardiac fibrosis. [PDF]
Kong M +7 more
europepmc +1 more source
Predicted <i>STAT1</i>-<i>BRAF</i> and <i>IRF7</i>-<i>MET</i> Regulatory Links Are Associated with MAPK Pathway Reactivation and Targeted Therapy Resistance in Melanoma. [PDF]
Fu H +6 more
europepmc +1 more source

