Results 1 to 10 of about 50,765 (160)
Structure-function relationships of the Mycobacterium tuberculosis transcription factor WhiB1. [PDF]
PLoS ONE, 2012 BackgroundMembers of the WhiB-like (Wbl) protein family possess iron-sulfur clusters and are implicated in the regulation of developmental processes in Actinomycetes. Mycobacterium tuberculosis possesses seven Wbl proteins.
Laura J Smith +3 more
doaj +10 more sources
Redox-Sensing Iron–Sulfur Cluster Regulators [PDF]
Antioxidants & Redox Signaling, 2018 Significance: Iron–sulfur cluster proteins carry out multiple functions, including as regulators of gene transcription/translation in response to environmental stimuli.
Crack, Jason C, Le Brun, Nick E
core +7 more sources
Erythropoiesis and Iron Sulfur Cluster Biogenesis [PDF]
Advances in Hematology, 2010 Erythropoiesis in animals is a synchronized process of erythroid cell differentiation that depends on successful acquisition of iron. Heme synthesis depends on iron through its dependence on iron sulfur (Fe-S) cluster biogenesis.
Hong Ye, Tracey A. Rouault
doaj +3 more sources
Mechanism of Iron–Sulfur Cluster Assembly: In the Intimacy of Iron and Sulfur Encounter
Inorganics, 2020 Iron–sulfur (Fe–S) clusters are protein cofactors of a multitude of enzymes performing essential biological functions. Specialized multi-protein machineries present in all types of organisms support their biosynthesis.
Batoul Srour +3 more
doaj +3 more sources
Structure of a Wbl protein and implications for NO sensing by M. tuberculosis [PDF]
Nature Communications, 2017 Mycobacterium tuberculosis WhiB1 is a DNA-binding protein with a NO sensitive [4Fe-4S] cluster. Here the authors present the NMR structure of WhiB1 and suggest how loss of the iron-sulfur cluster through nitrosylation affects WhiB1 DNA binding and leads ...
Bassam K. Kudhair +9 more
doaj +4 more sources
Modulation of MagR magnetic properties via iron–sulfur cluster binding
Scientific Reports, 2021 Iron–sulfur clusters are essential cofactors found in all kingdoms of life and play essential roles in fundamental processes, including but not limited to respiration, photosynthesis, and nitrogen fixation.
Zhen Guo +11 more
doaj +1 more source
Iron–sulfur cluster biosynthesis [PDF]
Biochemical Society Transactions, 2008 Iron–sulfur (Fe–S) clusters are present in more than 200 different types of enzymes or proteins and constitute one of the most ancient, ubiquitous and structurally diverse classes of biological prosthetic groups. Hence the process of Fe–S cluster biosynthesis is essential to almost all forms of life and is remarkably conserved in prokaryotic and ...
Sibali, Bandyopadhyay +2 more
openaire +2 more sources
Microbiology Spectrum, 2023 Iron-sulfur [Fe-S] clusters are one of the most ancient and functionally versatile natural biosynthetic prosthetic groups required by various proteins involved in important metabolic processes, including the oxidative phosphorylation of proteins ...
Xingju Song +5 more
doaj +1 more source
iScience, 2021 Summary: Mitochondria are a hallmark of eukaryal cells and play an important role in cellular metabolism. There is a vast amount of knowledge available on mitochondrial metabolism and essential mitochondrial functions, such as protein import and iron ...
Carl Malina +3 more
doaj +1 more source
Communications Chemistry, 2023 Iron-sulfur clusters are prosthetic groups of proteins involved in various biological processes. However, details of the immature state of the iron-sulfur cluster into proteins have not yet been elucidated. We report here the first structural analysis of
Erika Tsutsumi +9 more
doaj +1 more source