Results 171 to 180 of about 1,030,253 (321)

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

A Mitochondria‐Targeted Nanozyme Platform for Multi‐Pathway Tumor Therapy via Ferroptosis and Cuproptosis Regulation

open access: yesAdvanced Science, EarlyView.
This work reports a mitochondria‐targeted nanozyme platform, MIL‐Cu1.8S‐TPP/FA, which induces potent cuproptosis via localized delivery of Cu1.8S nanodots to mitochondria. Surface‐anchoring these nanodots onto MIL‐88B metal‐organic frameworks enhances both passive and active tumor targeting.
Chenguang Liu   +8 more
wiley   +1 more source

Iron chelation excludes protein synthesis inhibition in the tetracycline management of African trypanosomosis [PDF]

open access: green, 2005
Justine T. Ekanem   +3 more
openalex   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin   +9 more
wiley   +1 more source

Iron Chelation and Vascular Function [PDF]

open access: bronze, 2005
Dardo E. Ferrara, W. Robert Taylor
openalex   +1 more source

Role of Iron Chelators in Mucormycosis

open access: yesIndian Journal of Pharmacology, 2021
Vidya Mahalmani   +3 more
openaire   +3 more sources

Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li   +11 more
wiley   +1 more source

Event program [PDF]

open access: yes, 2011
UNLV Undergraduates from all departments, programs and colleges participated in a campus-wide symposium on April 16, 2011. Undergraduate posters from all disciplines and also oral presentations of research activities, readings and other creative ...
Reiber, Carl, Booker, Nicholle
core   +5 more sources

Treatment with hydroxyurea and iron chelation therapy in patients with hemoglobinopathies [PDF]

open access: bronze, 2005
Aurelio Maggio   +3 more
openalex   +1 more source

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