Results 41 to 50 of about 1,030,253 (321)

Synthesis and coordination chemistry of 2-(di-2-pyridylamino)pyrimidine; structural aspects of spin crossover in an Fe(II) complex [PDF]

, 2012
This paper was accepted on February 26 20122-(Di-2-pyridylamino)pyrimidine (L), a potentially ditopic tetradentate ligand, was synthesized from commercially available di-2-pyridylamine and 2-chloropyrimidine.
Addison, Amoore, Amoore, Antonioli, Atmani, Balzani, Barbour, Bloch, Boujemma Moubaraki, Brooker, Christopher J. Sumby, Domaga?a, Halcrow, Halcrow, Hayami, Janiak, Kaes, Keith S. Murray, Kharasch, Martin, Mosny, Murray, Murray, Neville, Neville, Olguin, Quesada, Quesada, Quesada, Rachel S. Crees, Real, Real, Ross, Ross, Sheldrick, Sumby, Sumby, Sumby, Sumby   +38 more
core   +2 more sources

Iron Chelation Therapy in Myelodysplastic Syndromes

Advances in Hematology, 2010
Myelodysplastic syndromes (MDS) are a heterogeneous disorder of the hematopoietic stem cells, frequently characterized by anemia and transfusion dependency. In low-risk patients, transfusion dependency can be long lasting, leading to iron overload.
Emanuela Messa, Daniela Cilloni, Giuseppe Saglio   +2 more
doaj   +1 more source

Bistable equilibrium points of mercury body burden [PDF]

, 2007
In the last century mercury levels in the global environment have tripled as a result of increased pollution from industrial, occupational, medicinal and domestic uses \cite{BaMe03}. Glutathione is known to be the main agent responsible for the excretion
Boulos, Areen, Owhadi, Houman
core   +2 more sources

Cardiac iron overload evaluation in thalassaemic patients using T2* magnetic resonance imaging following chelation therapy: a multicentre cross-sectional study

Hematology, Transfusion and Cell Therapy, 2023
Introduction: Magnetic resonance imaging (MRI) T2* technique is used to assess iron overload in the heart, liver and pancreas of thalassaemic patients. Optimal iron chelation and expected tissue iron response rates remain under investigation.
Eduardo Cerello Chapchap, Murilo Marques Almeida Silva, Reijane Alves de Assis, Lucila Nassif Kerbauy, Michelli da Silva Diniz, Laércio Alberto Rosemberg, Sandra Regina Loggetto, Aderson da Silva Araujo, Antonio Fabron Junior, Monica Pinheiro de Almeida Verissimo, Giorgio Roberto Baldanzi, Breno Pannia Esposito, Fernando Tricta, Merula Emmanoel Anargyrou Steagall, Claudia Ângela Galleni Di Sessa Vellozo, Kleber Yotsumoto Fertrin, Ronaldo Hueb Baroni, Nelson Hamerschlak   +17 more
doaj  

Naringin is a promising natural compound for therapy of iron-overload disorders

Brazilian Journal of Pharmaceutical Sciences, 2022
Naringin has been shown to exhibit satisfying iron chelation capacity. Considering the side effects of routinely-used iron chelator (desferrioxamine, DFO), we decided to evaluate the iron chelation potency of naringin to discover whether or not it can be
Mehrdad Jahanshahi, Masoumeh Khalili, Asra Margdari, Mahdi Aalikhani   +3 more
doaj   +1 more source

2D-ultrathin MXene/DOXjade platform for iron chelation chemo-photothermal therapy

Bioactive Materials, 2022
An increased demand for iron is a hallmark of cancer cells and is thought necessary to promote high cell proliferation, tumor progression and metastasis. This makes iron metabolism an attractive therapeutic target.
Yunjie Xu, Yingwei Wang, Jusung An, Adam C. Sedgwick, Mingle Li, Jianlei Xie, Weibin Hu, Jianlong Kang, Sajal Sen, Axel Steinbrueck, Bin Zhang, Lijun Qiao, Swelm Wageh, Jonathan F. Arambula, Liping Liu, Han Zhang, Jonathan L. Sessler, Jong Seung Kim   +17 more
doaj  

Challenges of Iron Chelation in Thalassemic Children

Thalassemia Reports
Thalassemia treatment still relies on supportive care, mainly including blood transfusion and iron chelation therapy. Iron chelation is considered the main factor responsible for the marked improvement in survival rates of thalassemic patients ...
Alkistis Adramerina, Marina Economou
doaj   +1 more source

A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS [PDF]

, 2011
International audienceTo better understand the detection and management of iron overload in transfusion-dependent patients with myelodysplastic syndromes (MDS), a 15-min web- or paper-based survey was conducted among 338 European physicians from 27 ...
Fenaux, Pierre,, Giagounidis, Aristoteles, Ille, Susanne, Leto Di Priolo, Susanna   +3 more
core   +4 more sources

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis. [PDF]

, 2020
Copper levels are known to be elevated in inflamed and malignant tissues. But the mechanism underlying this selective enrichment has been elusive. In this study, we report a axis by which inflammatory cytokines, such as IL-17, drive cellular copper ...
Bao, Shideng, Bulek, Katarzyna, Cai, Gang, Chang, Christopher J, Chen, Xing, Fox, Paul L, Huang, Emina, Jackson, Mark W, Jia, Shang, Kalady, Matthew F, Li, Xiaoxia, Liao, Yun, Pizarro, Theresa T, Sen, Ganes C, Stark, George R, Tang, Fangqiang, Zhao, Junjie   +16 more
core  

Durable Red Blood Cell Transfusion Independence in a Patient with an MDS/MPN Overlap Syndrome Following Discontinuation of Iron Chelation Therapy

Case Reports in Hematology, 2015
Background. Hematologic improvement (HI) occurs in some patients with acquired anemias and transfusional iron overload receiving iron chelation therapy (ICT) but there is little information on transfusion status after stopping chelation. Case Report.
Harpreet Kochhar, Chantal S. Leger, Heather A. Leitch   +2 more
doaj   +1 more source