Results 161 to 170 of about 1,910,895 (254)

Luspatercept in β‐thalassemia: Who and when. Strengths and weaknesses points of a real‐world evidence

eJHaem
Lorenza Torti, Nicolina Ardu, Laura Maffei, Paolo De Fabritiis, Francesco Sorrentino   +4 more
doaj   +1 more source

The role of tetramethylpyrazine and paeoniflorin in modulating iron metabolism and ferroptosis: innovative strategies for atherosclerosis treatment. [PDF]

Front Pharmacol
Zhang M, Wei W, Chen Z, Yan S, Wu Z, Lin Z, Yin H, Xu F.   +7 more
europepmc   +1 more source

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

Advanced Science, EarlyView.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang, Ziyang Tong, Chunmei Fan, Silong Chen, Jiarui Guo, Jianghua Hu, Ke Yao, Zi Yin, Xiao Chen, Yibo Yu   +9 more
wiley   +1 more source

The Genetics of Iron Metabolism on Biochemical and Hematological Phenotypes of Heart Failure. [PDF]

Int J Mol Sci
Barbosa M, Aguiar L, Matias A, Ferreira J, Caldeira J, Melício A, Faustino P, Falcão LM, Bicho M, Inácio Â.   +9 more
europepmc   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

Iron Metabolism in the Colorectal Tumor Microenvironment: From Preneoplastic Lesions to Cancer Progression. [PDF]

Int J Mol Sci
Tomoiagă AV, Suciu ȘM, Gerdanovics CA, Gerdanovics A, Milaciu MV, Perne MG, Alexescu TG, Ciumărnean L, Cozma A, Negrean V, Clichici SV, Orășan OH.   +11 more
europepmc   +1 more source

A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics

Advanced Science, EarlyView.
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma, Huimin Gong, Ran Zhuo, Zaixiao Rao, Yanxi Wan, Mingyang Wang, Zahra Zeinalzadeh, Yuan Gao, Aohan Guan, Xinrun Li, Wanting Chen, Xiliang Wang, Yun Wan, Sihua Zhang, Yuncai Xiao, Qi Huang, Paul R. Langford, Xiangru Wang, Rui Zhou, Rui Luo, Hongbo Zhou, Chengliang Zhu, Hui Jin   +22 more
wiley   +1 more source

Effects of Immunoadsorption on Markers of Iron Metabolism: A Case Series. [PDF]

J Clin Apher
Ginthör NE, Niedrist T, Schwantzer G, Kirsch AH, Ribitsch W, Deak A, Kolland M, Leitinger D, Eller K, Rosenkranz AR, Artinger K.   +10 more
europepmc   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Contrasting microbial iron metabolism in sediments from oxic and hypoxic estuaries. [PDF]

Front Microbiol
Du R, Xu C, Zhao D, Zeng H, Cheng Y, Tang K, Cai P, Zhang Y.   +7 more
europepmc   +1 more source