Results 231 to 240 of about 479,648 (301)

Relationship Between Hepcidin, Iron Metabolism, Inflammation and Hypersplenism in Anaemia of Kala-Azar. [PDF]

Parasite Immunol
Freitas AFA, Neto ASL, de Moura CMC, Silva GD, Silva MSABE, Vilges KMA, Ferreira FMAM, Costa DL, Costa CHN.   +8 more
europepmc   +1 more source

Injectable Chondroitin Sulfate Methacrylate Hydrogel Microspheres Co‐Loaded with GLPM Nanozyme, Dexamethasone, and Stem Cells for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng, Ying Fang, Hongwei Yu, Yicheng Wang, Yunze Xu, Chunxiao Shi, Haike Xia, Ranjith Kumar Kankala, Aizheng Chen, Shibin Wang, Chaoping Fu   +10 more
wiley   +1 more source

Interactions Between Iron Metabolism and the Endocannabinoid System in Bacterial Infections. [PDF]

Antibiotics (Basel)
Dickson KB, Zhou J, Lehmann C.
europepmc   +1 more source

Orthotopic liver transplantation for hemochromatosis [PDF]

, 1991
Kakizoe, S, Pillay, P, Starzl, TE, Tzakis, AG, Tzoracoleftherakis, E, Van Thiel, DH   +5 more
core  

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Mapping the genetic landscape of iron metabolism uncovers the SETD2 methyltransferase as a modulator of iron flux. [PDF]

Sci Adv
Martinelli AW, Wu CP, Vornbäumen T, Coates HW, Jordon LH, Wit N, Sia JJ, Speak AO, Nathan JA.   +8 more
europepmc   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Iron metabolism in rheumatic diseases. [PDF]

J Transl Autoimmun
Givian A, Azizan A, Jamshidi A, Mahmoudi M, Farhadi E.   +4 more
europepmc   +1 more source

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

Advanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang, Jingrui Wang, Qiaowan Chen, Chen Jiao, Yun Chen, Zhongshou Wu, Zhonghua Ma   +6 more
wiley   +1 more source

Additive effect of multiple genetic variants in <i>SEC23B</i> and <i>PIEZO1</i> on iron metabolism dyshomeostasis in hereditary anemias. [PDF]

Hemasphere
Nostroso A, Marra R, Rosato BE, Iscaro A, Esposito FM, D'Onofrio V, Dionisi M, Ribersani M, Giordano F, Bulla A, Del Vecchio GC, Scianguetta S, Mandrile G, Ceglie T, Scudiero O, Ferrero GB, Perrotta S, Iolascon A, Andolfo I, Russo R.   +19 more
europepmc   +1 more source