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Iron Homeostasis in the CNS: An Overview of the Pathological Consequences of Iron Metabolism Disruption

open access: yesInternational Journal of Molecular Sciences, 2022
Iron homeostasis disruption has increasingly been implicated in various neurological disorders. In this review, we present an overview of our current understanding of iron metabolism in the central nervous system. We examine the consequences of both iron
Tracey Rouault, Christina A Porras
exaly   +2 more sources

Iron Metabolism in Aging and Age-Related Diseases [PDF]

open access: yesInternational Journal of Molecular Sciences, 2022
Iron is a trace metal element necessary to maintain life and is also involved in a variety of biological processes. Aging refers to the natural life process in which the physiological functions of the various systems, organs, and tissues decline ...
Mingyao Yang   +2 more
exaly   +2 more sources

Iron metabolism

Current Opinion in Chemical Biology, 1999
The understanding of iron metabolism at the molecular level has been enormously expanded in recent years by new findings about the functioning of transferrin, the transferrin receptor and ferritin. Other recent developments include the discovery of the hemochromatosis gene HFE, identification of previously unknown proteins involved in iron transport ...
P, Aisen   +2 more
openaire   +2 more sources

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