Results 241 to 250 of about 479,648 (301)

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Iron metabolism disorder promotes postovulatory oocyte aging by inducing oxidative stress damage. [PDF]

Life Med
Huang Z, Wang B, Tian Y, Xu X, Zhang J, Lou S, Kang J, Zhang N, Song K, Li J, Weng J, Liang Y, Yang X, Ma W.   +13 more
europepmc   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

Iron metabolism and sepsis-associated liver injury: Methodological considerations and clinical perspectives. [PDF]

World J Hepatol
Koker G.
europepmc   +1 more source

Iron metabolism dysregulation and ferroptosis: Emerging drivers in pulmonary fibrosis pathogenesis and therapy. [PDF]

Mol Cells
Jiang Y, Zhang L, Lin Y, Zhu X, Wang T, Zhu Z, Chen Y, Tang D.   +7 more
europepmc   +1 more source

Association between BRINDA-corrected iron metabolism and lung function in the community: the CoLaus|PneumoLaus study. [PDF]

BMC Pulm Med
Touilloux B, Casutt A, Truong MK, Bongard C, Lechartier B, Marques-Vidal P, Vollenweider P, Vaucher J, von Garnier CV.   +8 more
europepmc   +1 more source

Effects of hydroxy methionine analog iron chelate on growth performance, blood parameters, and iron metabolism in weaned piglets. [PDF]

Sci Rep
Fu Y, Fang J, Ge Y, Zhang S, Liu Y, Zhou G, Yuan X, Jiao N, Li Y, Yang W.   +9 more
europepmc   +1 more source

Pulsed electromagnetic field prevents lumbar bone loss in orchiectomy mice without altering systemic iron metabolism. [PDF]

Front Bioeng Biotechnol
Yang J, Feng Y, Pan M, Zeng Y.
europepmc   +1 more source