Mechanically Regulated Nanozymes for Remote Metabolic Reprogramming and Precise Cancer Therapy
Inspired by mechanoenzymes, a ferrocene‐based mechanically regulated nanozyme converts acoustic shear force into enhanced peroxidase‐like activity by decreasing electron density and alleviating steric hindrance at the Fe active sites, thereby rewiring redox homeostasis. Leveraging this remote regulatory mechanism, a multienzyme‐regulated nanoreactor is
Fangman Chen +13 more
wiley +2 more sources
The Role of Iron in Neuronal Homeostasis: A Double-Edged Sword. [PDF]
Sgalletta B, Agostini F, Bisaglia M.
europepmc +1 more source
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa +6 more
wiley +1 more source
Advances in BODIPY Derivatives for Antibacterial Phototherapy
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv +9 more
wiley +2 more sources
Micronutrient Deficiencies in Heart Transplant Recipients-Scoping Review. [PDF]
Ławniczek M, Habryka J, Krupa-Nurcek S.
europepmc +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Circulating microRNA molecular signatures converge with erythroid phenotypes and iron homeostasis in pediatric tic disorders. [PDF]
Jia R +11 more
europepmc +1 more source
From gut-reproductive microbiota to ferroptosis: a comprehensive insight into the molecular-pathogenicity of endometriosis. [PDF]
Han X, Guo XL, Qiu J.
europepmc +1 more source
Ferroptosis in Neuropsychiatric and Neurodegenerative Disorders: Shared Mechanisms and Disease-Specific Signatures. [PDF]
Liu M, Zeng C, Si Z.
europepmc +1 more source
Ferroptosis at the crossroads of epilepsy and neurodegeneration. [PDF]
Khan SA, Qamar MA, Ali T.
europepmc +1 more source

