Results 71 to 80 of about 90,175 (271)
Chronic Fatigue Syndrome in Patients with Deteriorated Iron Metabolism
, 2022 Fatigue is a common, non-specific symptom that often impairs patients’ quality of life. Even though fatigue may be the first symptom of many serious diseases, it is often underestimated due to its non-specific nature.
Katarzyna Sikorska +11 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo +14 more
wiley +1 more source
Inherited disorders of iron metabolism
Pediatric Hematology/Oncology and Immunopathology, 2017 The presented review provides information about genetic diseases associated with impaired iron metabolism, includes the main aspects of normal iron metabolism, the mechanisms of its disruption for each described pathology. The review also presents information about major clinical manifestation, changes in laboratory parameters and the principles of ...
M. E. Lohmatova, N. S. Smetanina
openaire +1 more source
Regulation of hepcidin and hemojuvelin expression and their role in iron homeostasis
, 2010 Hepcidin is the key regulator of iron homeostasis acting as a negative regulator of intestinal iron absorption. Several proteins have recently been identified to act as upstream regulators of hepcidin expression, such as HFE and hemojuvelin (HJV ...
Salama, M.F.I.
core
Advanced Science, EarlyView.Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan +8 more
wiley +1 more source
, 2011 Ischemic heart disease, the main cause of mortality and morbidity in industrialized countries, is a metabolic phenomenon due to an inadequate oxygenation of heart tissue caused by the closing or narrowing of the coronary arteries.
Di Pascale, Antonio
core
Handbook of Iron Overload Disorders
, 2010 A practical, clinically-oriented handbook of iron overload disorders giving a compact guide to normal iron metabolism, iron-related pathobiology, and the diagnosis and management of heritable and acquired iron overload disorders.
Pradyumna D. Phatak +4 more
core +1 more source
Advanced Science, EarlyView.Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source
Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy
Smart MoleculesAcute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates. In the last 3 decades, the disruption of iron homeostasis and the cytotoxic effects mediated by iron have been ...
Xinyu Tan +4 more
doaj +1 more source
Advanced Science, EarlyView.This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu +18 more
wiley +1 more source