Results 11 to 20 of about 122,333 (295)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundSex‐related differences in cardiac function and iron metabolism exist in humans and experimental animals. Male patients and preclinical animal models are more susceptible to cardiomyopathies and heart failure.
Subhash K. Das +6 more
doaj +1 more source
Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis [PDF]
, 2018 Osteoporosis is associated with chronic iron overload secondary to hereditary hemochromatosis (HH), but the causative mechanisms are incompletely understood.
Camacho, António +7 more
core +4 more sources
International Journal of Hematology, 2011 A 66-year-old male patient presented with a 4-month history of progressive muscle weakness. Twelve years prior to presentation he was evaluated for fatigue, weight loss, new-onset diabetes and elevated liver enzymes and was diagnosed with hereditary hemochromatosis, homozygous for the C282Y mutation in the HFE gene.
Javier, Munoz +2 more
openaire +2 more sources
Iron(III)-chelating resins X. Iron detoxification of human plasma with iron(III)-chelating resins [PDF]
, 1993 Iron detoxification of human blood plasma was studied with resins containing desferrioxamine B (DFO) or 3-hydroxy-2-methyl-4(1H)-pyridinone (HMP) as iron(III)-chelating groups.
Bantjes, A., Does, L. van der, Feng, M.
core +6 more sources
Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]
, 2017 Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo +4 more
core +2 more sources
Iron overload and immunity [PDF]
, 2007 World J Gastroenterol. 2007 Sep 21;13(35):4707-15. Iron overload and immunity. Porto G, De Sousa M. Institute of Molecular and Cellular Biology, Rua do Campo Alegre, Porto 8234150, Portugal.
De Sousa, M., Porto, G.
core +1 more source
Protective effects of deferasirox and N-acetyl-L-cysteine on iron overload-injured bone marrow
Brazilian Journal of Medical and Biological Research, 2017 Using an iron overload mouse model, we explored the protective effect of deferasirox (DFX) and N-acetyl-L-cysteine (NAC) on injured bone marrow hematopoietic stem/progenitor cells (HSPC) induced by iron overload. Mice were intraperitoneally injected with
J.C. Shen, Y.C. Zhang, M.F. Zhao
doaj +1 more source
The Egyptian Journal of Radiology and Nuclear Medicine, 2018 Aim of the study: The aim of this study was to assess the utility of MRI as a non-invasive technique for grading of the hepatic and cardiac iron overload in Thalassemia patients in a cohort of patients in Alexandria, Egypt.
Sara K. Elfawal +2 more
doaj +1 more source
Identification of erythroferrone as an erythroid regulator of iron metabolism. [PDF]
, 2014 Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores.
Ganz, Tomas +5 more
core +1 more source
Bismuth coordination networks containing deferiprone: synthesis, characterisation, stability and antibacterial activity [PDF]
, 2015 A series of bismuth–dicarboxylate–deferiprone coordination networks have been prepared and structurally characterised. The new compounds have been demonstrated to release the iron overload drug deferiprone on treatment with PBS and have also been shown ...
An +28 more
core +2 more sources