Results 21 to 30 of about 1,016,828 (293)

Biopsy-based calibration of T2* magnetic resonance for estimation of liver iron concentration and comparison with R2 Ferriscan [PDF]

, 2014
There is a need to standardise non-invasive measurements of liver iron concentrations (LIC) so clear inferences can be drawn about body iron levels that are associated with hepatic and extra-hepatic complications of iron overload.
Alam, MH, Mohammed H Alam, He, T, Taigang He, Pennell, DJ, Gillian Smith, Carpenter, JP, Garbowski, MW, Dudley J Pennell, Maciej W Garbowski, John-Paul Carpenter, Porter, JB, John B Porter, Smith, G, Michael Roughton, Roughton, M   +15 more
core   +1 more source

Right ventricular volumes and function in thalassemia major patients in the absence of myocardial iron overload [PDF]

, 2010
Aim: We aimed to define reference ranges for right ventricular (RV) volumes, ejection fraction (EF) in thalassemia major patients (TM) without myocardial iron overload.Methods and results: RV volumes, EF and mass were measured in 80 TM patients who had ...
Maciej Garbowski, Maceira, A, Francisco Alpendurada, Banya Winston, He, T, Taigang He, Carpenter, JP, Smith, GC, Kirk, P, Shah, F, Maceira Alicia, Porter, JB, John B Porter, Banya, W, He Taigang, Walker, JM, Kirk Paul, Alicia Maceira, Alpendurada Francisco, Gillian C Smith, Porter John B, Smith Gillian C, Farrukh Shah, Pennell, DJ, Shah Farrukh, Pennell Dudley J, Deac Monica, Dudley J Pennell, Alpendurada, F, Paul Kirk, Winston Banya, Carpenter John-Paul, John-Paul Carpenter, Deac, M, J Malcolm Walker, Garbowski, M, Walker J Malcolm, Garbowski Maciej, Monica Deac   +38 more
core   +1 more source

Iron-overload myopathy [PDF]

International Journal of Hematology, 2011
A 66-year-old male patient presented with a 4-month history of progressive muscle weakness. Twelve years prior to presentation he was evaluated for fatigue, weight loss, new-onset diabetes and elevated liver enzymes and was diagnosed with hereditary hemochromatosis, homozygous for the C282Y mutation in the HFE gene.
Javier, Munoz, Natalia, Ferrari, Philip, Kuriakose   +2 more
openaire   +2 more sources

Assessment of hepatic and cardiac iron overload in thalassemia patients by magnetic resonance imaging: Our experience in Alexandria University

The Egyptian Journal of Radiology and Nuclear Medicine, 2018
Aim of the study: The aim of this study was to assess the utility of MRI as a non-invasive technique for grading of the hepatic and cardiac iron overload in Thalassemia patients in a cohort of patients in Alexandria, Egypt.
Sara K. Elfawal, Doaa M. Emara, Ahmed A. Shehata   +2 more
doaj   +1 more source

Multi-center transferability of a breath-hold T2 technique for myocardial iron assessment. [PDF]

, 2008
Background: Cardiac iron overload is the leading cause of death in thalassemia major and is usually assessed using myocardial T2* measurements. Recently a cardiovascular magnetic resonance (CMR) breath-hold T2 sequence has been developed as a possible ...
Tan, RS, Tan Ru, Chan, G.C.F, He, T, Fogel Mark A, Firmin David N, Au, W-Y, Pennell, Dudley J., Chan, GCF, Fogel, MA, Lam, W.M, Aydinok, Y, Chu, WCW, He, Taigang, Cohen, AR, Ng, I, Chu Winnie CW, Cohen, Alan R., Pennell, DJ, Pennell Dudley J, Firmin, D.N, Chu, W.C.W, Biceroglu, S, Fogel, M.A, Tan, R.S, Lam, WM, Chan Godfrey CF, Lam Wynnie M, Firmin, David N., Biceroglu Selen, Aydinok Yesim, Aydinok, Yesim, Firmin, DN, Kirk, Paul, Fogel, Mark A., Pennell, D.J, Ng Ivy, Kirk, P, Au, Wing-Yan, Tan, Ru San, Au, WY, He Taigang, Kirk Paul, Chan, GC, Biceroglu, Selen, Cohen, A.R, Au Wing-Yan, Chu, Winnie C. W., Chu, WC, Au, W.-Y, Lam, Wynnie M., Cohen Alan R, Ng, Ivy, Chan, Godfrey C. F., Taigang He, Godfrey CF Chan, Ru Tan, David N Firmin, Yesim Aydinok, Selen Biceroglu, Mark A Fogel, Winnie CW Chu, Wynnie M Lam, Ivy Ng, Wing-Yan Au, Dudley J Pennell, Paul Kirk, Alan R Cohen   +67 more
core   +1 more source

Brain iron content in systemic iron overload: a beta-thalassemia quantitative MRI study [PDF]

, 2019
Multisystem iron poisoning is a major concern for long-term beta-thalassemia management. Quantitative MRI-based techniques routinely show iron overload in heart, liver, endocrine glands and kidneys.
Concilio, Rosanna Di, Russo C., Femina G., Weiskopf, N. ; https://orcid.org/, Weiskopf N, Di Concilio R., Femina, Gianluca, Ciancio, Angela, Tartaglione I, Ponticorvo, Sara, Ciancio A, Esposito F., Manara, R., Tartaglione, I., Salle, Francesco Di, Ponticorvo S., Esposito, F., Manara, Renzo, Tartaglione, Immacolata, Russo C, Elefante A, Cirillo M., Cirillo M, Russo, C., Di Salle, F., Tartaglione I., Di Salle F, Carafa, Pasquale Alessandro, Manara R, De Michele E., De Michele, E., Femina G, Ciancio, A., De Michele, Elisa, Elefante A., Casale M, Carafa P. A., Casale, M., Ciancio A., Ponticorvo S, Weiskopf, Nikolaus, De Michele E, Perrotta S., Carafa, P., Perrotta S, Cirillo, Mario, Di Salle F., Di Concilio, R., Esposito F. Brain iron content in systemic iron overload: A beta-thalassemia quantitative MRI study, Esposito, Fabrizio, Perrotta, Silverio, Elefante, Andrea, Weiskopf N., Russo, Camilla, Perrotta, S., Di Concilio R, Ponticorvo, S., Femina, G., Manara R., Cirillo, M., Casale, Maddalena, Casale M., Elefante, A., Carafa PA   +63 more
core   +1 more source

Safety Aspects of Iron in Food [PDF]

, 2001
During the last decades efforts regarding dietary iron supply focused mostly on the prevention of deficiencies, especially during growth and pregnancy.
Schümann, Klaus
core   +1 more source

Biophysical and Cell Biological Studies Characterizing the Vertebrate Iron Exporter Ferroportin [PDF]

, 2009
Mammalian iron homeostasis is maintained by an intricate network of diverse proteins that constantly survey systemic iron levels and carefully regulate the uptake of iron from the diet. Control of this uptake is critically important because once iron is
Rice, Adrian Edward
core   +1 more source

Is iron overload associated with worse outcomes in patients with chronic liver disease undergoing liver transplantation?

Revista de Investigación Clínica
Background: Iron overload is frequent in patients with chronic liver disease, associated with shorter survival after liver transplantation in patients with hereditary hemochromatosis.
Sergio Rodriguez-Rodriguez, Antonio Olivas-Martínez, Jesus Delgado-de la Mora, Braulio Martinez-Benitez, Ignacio García-Juarez, Roberta Demichelis-Gómez   +5 more
doaj   +1 more source

Neuroprotective Role of α-Lipoic Acid in Iron-Overload-Mediated Toxicity and Inflammation in In Vitro and In Vivo Models

Antioxidants, 2022
Hemoglobin and iron overload is considered the major contributor to intracerebral hemorrhage (ICH)-induced brain injury. Accumulation of iron in the brain leads to microglia activation, inflammation and cell loss.
Giuseppe Carota, Alfio Distefano, Mariarita Spampinato, Cesarina Giallongo, Giuseppe Broggi, Lucia Longhitano, Giuseppe A. Palumbo, Rosalba Parenti, Rosario Caltabiano, Sebastiano Giallongo, Michelino Di Rosa, Riccardo Polosa, Vincenzo Bramanti, Nunzio Vicario, Giovanni Li Volti, Daniele Tibullo   +15 more
doaj   +1 more source