Results 21 to 30 of about 966,431 (294)

Biophysical and Cell Biological Studies Characterizing the Vertebrate Iron Exporter Ferroportin [PDF]

, 2009
Mammalian iron homeostasis is maintained by an intricate network of diverse proteins that constantly survey systemic iron levels and carefully regulate the uptake of iron from the diet. Control of this uptake is critically important because once iron is
Rice, Adrian Edward
core   +1 more source

Safety Aspects of Iron in Food [PDF]

, 2001
During the last decades efforts regarding dietary iron supply focused mostly on the prevention of deficiencies, especially during growth and pregnancy.
Schümann, Klaus
core   +1 more source

Iron Status Predicts Treatment Failure and Mortality in Tuberculosis Patients: A Prospective Cohort Study from Dar es Salaam, Tanzania. [PDF]

, 2012
Experimental data suggest a role for iron in the course of tuberculosis (TB) infection, but there is limited evidence on the potential effects of iron deficiency or iron overload on the progression of TB disease in humans. The aim of the present analysis
Spiegelman Donna, Sheila Isanaka, Walter C Willett, Mugusi Ferdinand, Isanaka Sheila, Isanaka, Sheila, Wafaie W Fawzi, Fawzi, Wafaie, Spiegelman, Donna, Christopher Duggan, Fawzi Wafaie W., Bosch, Ronald J, Said Aboud, Bosch Ronald J., Willett Walter C., Willett, Walter C, Aboud, Said, Ferdinand Mugusi, Mugusi, Ferdinand, Aboud Said, Ronald J Bosch, Duggan Christopher, Duggan, Christopher, Bosch, Ronald, Donna Spiegelman, Willett, Walter, Fawzi, Wafaie W   +26 more
core   +2 more sources

Orchestrated regulation of iron trafficking proteins in the kidney during iron overload facilitates systemic iron retention. [PDF]

PLoS ONE, 2018
The exact route of iron through the kidney and its regulation during iron overload are not completely elucidated. Under physiologic conditions, non-transferrin and transferrin bound iron passes the glomerular filter and is reabsorbed through kidney ...
Avital Weiss, Lior Spektor, Lyora A Cohen, Lena Lifshitz, Inbar Magid Gold, De-Liang Zhang, Marianna Truman-Rosentsvit, Yael Leichtmann-Bardoogo, Abraham Nyska, Sefi Addadi, Tracey A Rouault, Esther G Meyron-Holtz   +11 more
doaj   +1 more source

Neuroprotective Role of α-Lipoic Acid in Iron-Overload-Mediated Toxicity and Inflammation in In Vitro and In Vivo Models

Antioxidants, 2022
Hemoglobin and iron overload is considered the major contributor to intracerebral hemorrhage (ICH)-induced brain injury. Accumulation of iron in the brain leads to microglia activation, inflammation and cell loss.
Giuseppe Carota, Alfio Distefano, Mariarita Spampinato, Cesarina Giallongo, Giuseppe Broggi, Lucia Longhitano, Giuseppe A. Palumbo, Rosalba Parenti, Rosario Caltabiano, Sebastiano Giallongo, Michelino Di Rosa, Riccardo Polosa, Vincenzo Bramanti, Nunzio Vicario, Giovanni Li Volti, Daniele Tibullo   +15 more
doaj   +1 more source

Is iron overload associated with worse outcomes in patients with chronic liver disease undergoing liver transplantation?

Revista de Investigación Clínica
Background: Iron overload is frequent in patients with chronic liver disease, associated with shorter survival after liver transplantation in patients with hereditary hemochromatosis.
Sergio Rodriguez-Rodriguez, Antonio Olivas-Martínez, Jesus Delgado-de la Mora, Braulio Martinez-Benitez, Ignacio García-Juarez, Roberta Demichelis-Gómez   +5 more
doaj   +1 more source

Impact of iron overload on interleukin-10 levels, biochemical parameters and oxidative stress in patients with sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia, 2013
OBJECTIVE: The aim of this study was to evaluate the impact of iron overload on the profile of interleukin-10 levels, biochemical parameters and oxidative stress in sickle cell anemia patients.
Maritza Cavalcante Barbosa, Talyta Ellen Jesus dos Santos, Geane Félix de Souza, Lívia Coêlho de Assis, Max Victor Carioca Freitas, Romélia Pinheiro Gonçalves   +5 more
doaj   +3 more sources

Calibration of myocardial T2 and T1 against iron concentration. [PDF]

, 2014
BACKGROUND: The assessment of myocardial iron using T2* cardiovascular magnetic resonance (CMR) has been validated and calibrated, and is in clinical use.
Timothy G St. Pierre, St Pierre, TG, Firmin, DN, Forni, G, Mary N Sheppard, Fleming, A, Gualtiero Catani, He, T, Gianluca Forni, Taigang He, House, M, Sofia V de Noronha, Carpenter, JP, Black, G, Walker, J, Sheppard, MN, Kirk, P, Baksi, AJ, John C Wood, Porter, JB, John B Porter, Mike House, Walker, JM, Fucharoen, S, Wood, JC, Suthat Fucharoen, A John Baksi, Pennell, DJ, Adam Fleming, Greg Black, Anderson, LJ, Baksi, A, Dudley J Pennell, Paul Kirk, Lisa J Anderson, David N Firmin, John-Paul Carpenter, J Malcolm Walker, Gildo Matta, Michael Roughton, Roughton, M, de Noronha, SV, Matta, G, Catani, G   +43 more
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Absence of gut microbiota alleviates iron overload-induced colitis by modulating ferroptosis in mice

Journal of Advanced Research
Introduction: Iron overload disrupts gut microbiota and induces ferroptosis, contributing to colitis. However, whether gut microbiota directly drives iron overload-induced colitis and its underlying mechanism remain unclear.
Ke Gu, Aimin Wu, Chen Liu, Bing Yu, Jun He, Xin Lai, Junzhou Chen, Yuheng Luo, Hui Yan, Ping Zheng, Junqiu Luo, Junning Pu, Quyuan Wang, Huifen Wang, Daiwen Chen   +14 more
doaj   +1 more source

Ameliorating Iron Overload in Intestinal Tissue of Adult Male Rats: Quercetin vs Deferoxamine

Journal of Toxicology, 2018
Objective. The aim of our study is to compare the role of the new natural alternative (Quercetin) with the current iron-chelation therapy (Deferoxamine (DFO)) in the effect of iron overload on small intestinal tissues and to investigate the possible ...
Arwa A. El-Sheikh, Shimaa Hamed Ameen, Samaa Salah AbdEl-Fatah   +2 more
doaj   +1 more source