Results 21 to 30 of about 57,543 (289)
The Egyptian Journal of Radiology and Nuclear Medicine, 2018 Aim of the study: The aim of this study was to assess the utility of MRI as a non-invasive technique for grading of the hepatic and cardiac iron overload in Thalassemia patients in a cohort of patients in Alexandria, Egypt.
Sara K. Elfawal +2 more
doaj +1 more source
Orchestrated regulation of iron trafficking proteins in the kidney during iron overload facilitates systemic iron retention. [PDF]
PLoS ONE, 2018 The exact route of iron through the kidney and its regulation during iron overload are not completely elucidated. Under physiologic conditions, non-transferrin and transferrin bound iron passes the glomerular filter and is reabsorbed through kidney ...
Avital Weiss +11 more
doaj +1 more source
Antioxidants, 2022 Hemoglobin and iron overload is considered the major contributor to intracerebral hemorrhage (ICH)-induced brain injury. Accumulation of iron in the brain leads to microglia activation, inflammation and cell loss.
Giuseppe Carota +15 more
doaj +1 more source
Revista de Investigación ClínicaBackground: Iron overload is frequent in patients with chronic liver disease, associated with shorter survival after liver transplantation in patients with hereditary hemochromatosis.
Sergio Rodriguez-Rodriguez +5 more
doaj +1 more source
Revista Brasileira de Hematologia e Hemoterapia, 2013 OBJECTIVE: The aim of this study was to evaluate the impact of iron overload on the profile of interleukin-10 levels, biochemical parameters and oxidative stress in sickle cell anemia patients.
Maritza Cavalcante Barbosa +5 more
doaj +3 more sources
Ameliorating Iron Overload in Intestinal Tissue of Adult Male Rats: Quercetin vs Deferoxamine
Journal of Toxicology, 2018 Objective. The aim of our study is to compare the role of the new natural alternative (Quercetin) with the current iron-chelation therapy (Deferoxamine (DFO)) in the effect of iron overload on small intestinal tissues and to investigate the possible ...
Arwa A. El-Sheikh +2 more
doaj +1 more source
Absence of gut microbiota alleviates iron overload-induced colitis by modulating ferroptosis in mice
Journal of Advanced ResearchIntroduction: Iron overload disrupts gut microbiota and induces ferroptosis, contributing to colitis. However, whether gut microbiota directly drives iron overload-induced colitis and its underlying mechanism remain unclear.
Ke Gu +14 more
doaj +1 more source
Hematology, 2005 Iron is one of the most common elements in nature. As a transition metal it is very efficient in electron transport and redox reactions. The proteins and enzymes in which iron is an essential component play a key role in respiration, energy production, detoxification of harmful oxygen species and cell replication.
Chaim, Hershko +3 more
openaire +2 more sources
Case Reports in Oncology, 2020 Iron overload is commonly seen in the context of hematological diseases in patients who require frequent transfusions. On the other hand, an association between autoimmune hemolytic anemia complicating chronic lymphocytic leukemia and iron overload is ...
Mohammad Ali, Mohamed A. Yassin
doaj +1 more source
Current Review of Iron Overload and Related Complications in Hematopoietic Stem Cell Transplantation
Turkish Journal of Hematology, 2017 Iron overload is an adverse prognostic factor for patients undergoing hematopoietic stem cell transplantation (HSCT). In the HSCT setting, pretransplant and early posttransplant ferritin and transferrin saturation were found to be highly elevated due to ...
Erden Atilla +2 more
doaj +1 more source