Results 31 to 40 of about 1,016,828 (293)
Assessing iron overload: Are we there yet? [PDF]
, 2012 Iron overload occurs in many hematologic disorders and causes significant morbidity. The advantages of MRI in quantifying liver iron concentration continue to mount, and the association between iron overload and increased mortality after allogeneic stem ...
M. Leahy (12582478) +2 more
core +2 more sources
Do H63D homozygote patients have clinically significant iron overload?
, 2011 Homozygosity H63D is present in 2% of the normal Caucasian population and is thought to carry a small risk of iron overload.
J. R. White +11 more
core +1 more source
The role of NCOA4-mediated ferritinophagy in iron overload [PDF]
, 2023 Iron homeostasis is a vital process that balances access to free iron to fuel physiological processes with iron storage to reduce the deleterious aspects of excess free iron.
Dorman, Matthew J.
core +1 more source
Hematology, 2005 Iron is one of the most common elements in nature. As a transition metal it is very efficient in electron transport and redox reactions. The proteins and enzymes in which iron is an essential component play a key role in respiration, energy production, detoxification of harmful oxygen species and cell replication.
Chaim, Hershko +3 more
openaire +2 more sources
Revista Brasileira de Hematologia e Hemoterapia, 2013 OBJECTIVE: The aim of this study was to evaluate the impact of iron overload on the profile of interleukin-10 levels, biochemical parameters and oxidative stress in sickle cell anemia patients.
Maritza Cavalcante Barbosa +5 more
doaj +3 more sources
Ameliorating Iron Overload in Intestinal Tissue of Adult Male Rats: Quercetin vs Deferoxamine
Journal of Toxicology, 2018 Objective. The aim of our study is to compare the role of the new natural alternative (Quercetin) with the current iron-chelation therapy (Deferoxamine (DFO)) in the effect of iron overload on small intestinal tissues and to investigate the possible ...
Arwa A. El-Sheikh +2 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
The evaluation of iron deficiency and iron overload
Deutsches Ärzteblatt international, 2021 In the western world, 10-15% of women of child-bearing age suffer from iron-deficiency anemia. Iron overload due to chronic treatment with blood transfusions or hereditary hemochromatosis is much rarer.This review is based on pertinent publications retrieved by a selective search on the pathophysiology, clinical features, and diagnostic evaluation of ...
Norbert, Gattermann +4 more
openaire +2 more sources
Genetic haemochromatosis: diagnosing and treating hereditary iron overload
, 2017 Genetic haemochromatosis (GH) is the most common inherited genetic disorder in caucasians, affecting approximately 1 in every 200–250 people. It leads to an increased absorption and deposition of iron, and if it is untreated it can cause systemic iron ...
Gerri Mortimore, Mortimore, Gerri
core +1 more source
Advanced Engineering Materials, EarlyView.The present work reports the microstructural, mechanical, and texture evolution of a dissimilar combination laser‐welded maraging steel with 4340 steel. This is important for aerospace applications. The demand for dissimilar welding is growing rapidly with the requirement of efficient and durable joints.
Bharat Behl +3 more
wiley +1 more source