Results 31 to 40 of about 966,431 (294)
Hematology, 2005 Iron is one of the most common elements in nature. As a transition metal it is very efficient in electron transport and redox reactions. The proteins and enzymes in which iron is an essential component play a key role in respiration, energy production, detoxification of harmful oxygen species and cell replication.
Chaim, Hershko +3 more
openaire +2 more sources
Do H63D homozygote patients have clinically significant iron overload?
, 2011 Homozygosity H63D is present in 2% of the normal Caucasian population and is thought to carry a small risk of iron overload.
J. R. White +11 more
core +1 more source
Current Review of Iron Overload and Related Complications in Hematopoietic Stem Cell Transplantation
Turkish Journal of Hematology, 2017 Iron overload is an adverse prognostic factor for patients undergoing hematopoietic stem cell transplantation (HSCT). In the HSCT setting, pretransplant and early posttransplant ferritin and transferrin saturation were found to be highly elevated due to ...
Erden Atilla +2 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Curcumin Attenuates Iron Accumulation and Oxidative Stress in the Liver and Spleen of Chronic Iron-Overloaded Rats. [PDF]
PLoS ONE, 2015 Iron overload is now recognized as a health problem in industrialized countries, as excessive iron is highly toxic for liver and spleen. The potential use of curcumin as an iron chelator has not been clearly identified experimentally in iron overload ...
Farid A Badria +3 more
doaj +1 more source
The evaluation of iron deficiency and iron overload
Deutsches Ärzteblatt international, 2021 In the western world, 10-15% of women of child-bearing age suffer from iron-deficiency anemia. Iron overload due to chronic treatment with blood transfusions or hereditary hemochromatosis is much rarer.This review is based on pertinent publications retrieved by a selective search on the pathophysiology, clinical features, and diagnostic evaluation of ...
Norbert, Gattermann +4 more
openaire +2 more sources
Genetic haemochromatosis: diagnosing and treating hereditary iron overload
, 2017 Genetic haemochromatosis (GH) is the most common inherited genetic disorder in caucasians, affecting approximately 1 in every 200–250 people. It leads to an increased absorption and deposition of iron, and if it is untreated it can cause systemic iron ...
Gerri Mortimore, Mortimore, Gerri
core +1 more source
Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi +6 more
wiley +1 more source
Case Reports in Oncology, 2020 Iron overload is commonly seen in the context of hematological diseases in patients who require frequent transfusions. On the other hand, an association between autoimmune hemolytic anemia complicating chronic lymphocytic leukemia and iron overload is ...
Mohammad Ali, Mohamed A. Yassin
doaj +1 more source
Antioxidant effect of selenium and its Nano form on oxidative stress induced by iron overload [PDF]
Benha Veterinary Medical Journal, 2016 The aim of this study was to demonstrate the antioxidant effect of selenium in its ordinary and Nano form on oxidativestress induced by iron overload in male rat. This study was carried out on 90 rat, weighted 180-200 gm.
Samah Algharib +3 more
doaj +1 more source