Results 31 to 40 of about 50,429 (161)
Scientific Reports, 2022 Hepatic iron overload is often concurrent with nonalcoholic fatty liver disease (NAFLD). Dysmetabolic iron overload syndrome (DIOS) is characterized by an increase in the liver and body iron stores and metabolic syndrome components.
Sakura Fujiwara +5 more
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Health Science ReportsBackground and Aims Chronic kidney disease (CKD) patients undergoing peritoneal dialysis (PD) are susceptible to complications, including iron overload, which can significantly impact their prognosis and overall health. This scoping review aimed to study
Abdulqadir J. Nashwan +5 more
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BMC Medical Imaging, 2022 Background Iron overload plays a critical role in the pathogenesis of diabetic nephropathy. Non-invasive evaluation of renal iron overload in diabetes in the management and intervention of diabetic nephropathy is of great significance.
Weiwei Geng +7 more
doaj +1 more source
Acta Medica Indonesiana, 2018 Background: routine blood transfusion in transfusion-dependent-thalassemia (TDT) causes iron accumulation in various organ. Serum markers of iron overload, serum ferritin and transferrin saturation, are sensitive but not specific.
Pustika Amalia Wahidiyat +2 more
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The corrected QT interval prolongation in adolescents with cardiac iron overload β-thalassemia major
The Turkish Journal of Pediatrics, 2020 Background and Objectives. Iron-induced cardiomyopathy remains the leading cause of mortality in β-thalassemia major patients. The T2* magnetic resonance imaging (MRI) technique is the gold standard for iron load detection, yet it is expensive and
Najib Advani +2 more
doaj +1 more source
Clinics in Liver Disease, 1998 Hereditary hemochromatosis is a common disorder of iron metabolism that increasingly is diagnosed and treated prior to the development of cirrhosis or diabetes. The discovery of a candidate gene for hereditary hemochromatosis undoubtedly will result in improved diagnosis of hereditary hemochromatosis and to a better understanding of certain aspects of ...
openaire +2 more sources
Iron overload in Montpelier [PDF]
Gut, 2001 See article on page 836 Since the original discovery of the haemochromatosis gene (HFE) in 1996,1 there have been two genetic mutations that have dominated clinical studies. The C282Y mutation (845 G→A) has attracted the most attention as the majority of typical haemochromatosis patients are homozygotes for this mutation. This has increasingly led to
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World Journal of Gastroenterology, 2007 Progress in the characterization of genes involved in the control of iron homeostasis in humans and in mice has improved the definition of iron overload and of the cells affected by it. The cell involved in iron overload with the greatest effect on immunity is the macrophage.
Graça, Porto, Maria, De Sousa
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Cardiac injury caused by iron overload in thalassemia
Frontiers in PediatricsCardiac iron overload affects approximately 25% of patients with β-thalassemia major, which is associated with increased morbidity and mortality.
Chunxi Fu, Chunxi Fu, Xue Yang, Xue Yang
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Hepatology Communications, 2017 Iron overload causes the generation of reactive oxygen species that can lead to lasting damage to the liver and other organs. The goal of this study was to identify genes that modify the toxicity of iron overload.
Tiago Koppe +9 more
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