Results 51 to 60 of about 50,429 (161)

Lysosomal iron accumulation and subsequent lysosomes-mitochondria iron transmission mediate PFOS-induced hepatocyte ferroptosis

Ecotoxicology and Environmental Safety
Perfluorooctane sulfonate (PFOS) is known as a persistent organic pollutant. A significant correlation between PFOS and liver ferroptosis has been unveiled, but the precise mechanism needs to be elucidated. In prior research, we found that PFOS treatment
Jixun Li, Ruzhen Feng, Wei Yang, Peiyao Liang, Tianming Qiu, Jingyuan Zhang, Xiance Sun, Qiujuan Li, Guang Yang, Xiaofeng Yao   +9 more
doaj   +1 more source

Iron Deficiency and Iron Overload [PDF]

Archives of Disease in Childhood, 1965
, SMITH, , RS
openaire   +2 more sources

Iron Metabolism in Patients with Paroxysmal Nocturnal Hemoglobinuria: Results of a Single-Center Ambispective Clinical Trial

Клиническая онкогематология
BACKGROUND. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal hematologic disease manifesting among others in hemolytic anemia. Due to predominantly intravascular hemolysis, iron metabolism in PNH patients is characterized by a number of ...
Vitalii Dmitrievich Latyshev, K. A. Jennewein, A. A. Soloveva, A. E. Kitsenko, N. V. Tsvetaeva, E. A. Lukina   +5 more
doaj   +1 more source

Mycobacterium avium Complex Infection in a Patient with Sickle Cell Disease and Severe Iron Overload

Case Reports in Infectious Diseases, 2014
A 34-year-old female with sickle cell anemia (hemoglobin SS disease) and severe iron overload presented to our institution with the subacute presentation of recurrent pain crisis, fever of unknown origin, pancytopenia, and weight loss.
Kamal Shemisa, Nasima Jafferjee, David Thomas, Gretta Jacobs, Howard J. Meyerson   +4 more
doaj   +1 more source

Iron overload [PDF]

Postgraduate Medical Journal, 1969
openaire   +2 more sources

Severe Iron Overload [PDF]

Clinical Gastroenterology and Hepatology, 2019
Manhal Izzy, Patrick S. Kamath
openaire   +2 more sources

Inhibition of Slc39a14/Slc39a8 reduce vascular calcification via alleviating iron overload induced ferroptosis in vascular smooth muscle cells

Cardiovascular Diabetology
Background Vascular calcification (VC) is an independent risk factor for cardiovascular diseases. Recently, ferroptosis has been recognised as a novel therapeutic target for cardiovascular diseases.
Yierpani Aierken, Huqiang He, Runwen Li, Zipeng Lin, Tongjie Xu, Li Zhang, Ya Wu, Yong Liu   +7 more
doaj   +1 more source

Transfusional iron overload [PDF]

Clinical & Laboratory Haematology, 1985
R E, Marcus, E R, Huehns
openaire   +2 more sources

Iron overload

Medicina Universitaria, 2015
The normal iron content of the body is 3---4 g. It exists in hemoglobin, in iron-containing proteins different to hemoglobin, in iron bound to transferrin in plasma, and in the form of ferritin and hemosiderin. There is approximately 1 g of storage iron, mostly in liver, spleen, and bone marrow.
openaire   +2 more sources

The role of mitochondria in iron overload-induced damage

Journal of Translational Medicine
Iron overload is a pathological condition characterized by the abnormal accumulation of iron within the body, which may result from excessive iron intake, disorders of iron metabolism, or specific disease states.
Yangyang Zhao, Mengjiao Yang, Xiaoxue Liang   +2 more
doaj   +1 more source