Results 91 to 100 of about 16,503 (251)

Development of Synergetic Combinations of a Novel Apoptosis Inducer with AKT and Hsp90 Selective Inhibitors Targeting Hormone-Sensitive and Hormone-Resistant Breast Cancer Cells

open access: yesProceedings
Introduction: The design and development of antitumor compounds based on an isatin core led to the synthesis of 1-substituted isatin-5-sulfonamides with potent antiproliferative activity [...]
Diana I. Salnikova   +7 more
doaj   +1 more source

Intestinal Microbiota, Probiotics and Mental Health: From Metchnikoff to Modern Advances: Part III – Convergence toward Clinical Trials [PDF]

open access: yes, 2013
Rapid scientific and technological advances have allowed for a more detailed understanding of the relevance of intestinal microbiota, and the entire body-wide microbiome, to human health and well-being.
Bested, Alison C   +2 more
core   +2 more sources

Design, synthesis and anticonvulsant activity of some new 5,7-dibromoisatin semicarbazone derivatives [PDF]

open access: yes, 2013
A series of 5,7-dibromoisatin semicarbazones have been synthesized in good yield, involving aryl urea and aryl semicarbazide formation. The structures of the synthesized compounds were confirmed on the basis of their spectral data. All the compounds were
Kumar, Dheeraj   +6 more
core  

Microporous Polymer Networks for Carbon Capture Applications [PDF]

open access: yes, 2018
Producción CientíficaA new generation of porous polymer networks has been obtained in quantitative yield by reacting two rigid trifunctional aromatic monomers (1,3,5-triphenylbenzene and triptycene) with two ketones having electron-withdrawing groups ...
Aguilar Lugo, Carla   +7 more
core   +2 more sources

N-Alkyl-Substituted Isatins Enhance P2X7 Receptor-Induced Interleukin-1β Release from Murine Macrophages

open access: yesMediators of Inflammation, 2016
Extracellular adenosine 5′-triphosphate (ATP) activates the P2X7 receptor channel to induce the rapid release of the proinflammatory cytokine, interleukin- (IL-) 1β, from macrophages. Microtubule rearrangements are thought to be involved in this process.
Ronald Sluyter, Kara L. Vine
doaj   +1 more source

Advances in Mechanochemical Methods for One‐Pot Multistep Organic Synthesis

open access: yesChemistry – A European Journal, Volume 31, Issue 34, June 17, 2025.
This review highlights recent advances in mechanochemical methods for multistep organic synthesis, focusing on sequential one‐pot approaches performed by grinding or ball milling. The presented transformations are discussed in terms of efficiency, applicability, and sustainability, assessing both the challenges and potential of solvent‐free one‐pot ...
Nina Biedermann, Michael Schnürch
wiley   +1 more source

Investigation of potential anti-radiation and anti-neoplastic compounds related to plant growth regulators second quarterly progress report, 1 oct. 1964 - 1 jan. 1965 [PDF]

open access: yes
Antiradiation and antineoplastic compounds related to plant growth regulators - cytotoxic effects and radiation ...
Norman, D., Schultz, R. D.
core   +1 more source

Organocatalytic Enantioselective Friedel-Crafts Aminoalkylation of Indoles in the Carbocyclic Ring [PDF]

open access: yes, 2016
The first general catalytic method for the, so far elusive, enantioselective Friedel−Crafts functionalization of indoles in the carbocyclic ring is presented.
Blay Llinares, Gonzalo   +6 more
core   +6 more sources

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