Results 91 to 100 of about 23,803 (294)
ProceedingsIntroduction: The design and development of antitumor compounds based on an isatin core led to the synthesis of 1-substituted isatin-5-sulfonamides with potent antiproliferative activity [...]
Diana I. Salnikova +7 more
doaj +1 more source
Condensation of Indole with Isatin over AlCl3/Mesoporous Aluminosilicate
Indonesian Journal of Chemistry, 2015 Aluminium chloride immobilized on mesoporous aluminosilicate was investigated as catalysts in the condensation of isatin with indole. AlCl3/mesoporous aluminosilicate (AlCl3/AM) catalysts were prepared by impregnation of 1, 5, 10 and 15 wt% AlCl3 on the ...
Tri Esti Purbaningtias +6 more
doaj +1 more source
Organo‐, Metal‐, and Enzyme‐Mediated Stereoselective Transformations of α‐Angelica Lactone
ChemCatChem, Volume 17, Issue 10, May 22, 2025.α‐Angelica lactone is a readily available small molecule from biomass source, which, coupled with cheapness and versatile reactivity, attracted significant interest for applications in asymmetric synthesis. In this minireview, stereoselective organo‐, metal‐, and enzymatic‐based approaches for the construction of new butenolide‐containing heterocycles,
Amina Moutayakine +2 more
wiley +1 more source
Synthesis, antimicrobial, anticancer, antiviral evaluation and QSAR studies of 4-(1-aryl-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substituted benzene sulfonamides [PDF]
, 2014 A series of 4-(1-aryl-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substituted benzenesulfonamide derivatives (1–32) was synthesized and evaluated for its in vitro antimicrobial, antiviral and cytotoxic activities.
Clercq, Erik De +6 more
core +2 more sources
Hypoxia in the Initiation and Progression of Neuroblastoma Tumours [PDF]
, 2020 Neuroblastoma is the most frequent extracranial solid tumour in children, causing 10% of all paediatric oncology deaths. It arises in the embryonic neural crest due to an uncontrolled behaviour of sympathetic nervous system progenitors, giving rise to ...
Gómez Muñoz, María Ángeles +3 more
core +1 more source
Skeletal Rearrangements of Amides via Breaking Inert Bonds
Chemistry – A European Journal, Volume 31, Issue 25, May 5, 2025.This review highlights advances in amide skeletal rearrangement reactions over the past two decades, categorized by the initial bond cleavages: C─N bond cleavage, C─C bond cleavage, and C═O bond activation. It summarizes emerging strategies, mechanistic insights, and synthetic applications, providing a focused perspective on recent developments in this
Rui Zhang, Guangbin Dong
wiley +1 more source
Neurohormonok, neuropeptidek szerepe az idegrendszer és az endokrin rendszer adaptatív működésének szabályozásában = The role of neurohormones and neuropeptides in the regulation of the adaptive function of the neural and endocrine system [PDF]
, 2006 Összefoglalás A vizsgált periodusban a vállalt feladat több neuropeptidnek mint a PACAP 38, orexin A és B endomorphin-1, a MERF, apelin-13, urocortin 1 , 2 és 3, valamint a ghrelinnek vizsgálata olyan idegrendszeri funkciókban mint a tanulás és ...
Gecse, Árpád +8 more
core
The structure of isatin―I [PDF]
Proceedings of the Royal Society of London. Series A - Mathematical and Physical Sciences, 1936 The constitution of isatin has long presented a problem of considerable interest. This substance may react either as a lactam (I) or as a lactim (II), giving rise, for example, to two quite distinct methyl ethers, the nitrogen-ether (III) or the somewhat unstable oxygen-ether (IV).
Thomas Henry Goodwin +2 more
openaire +2 more sources
ChemistrySelect, Volume 10, Issue 17, May 5, 2025.A new set of spirooxindole‐ and spiroindenoquinoxaline‐derived pyrrolo[3,4‐c] pyrroles has been synthesized through atom‐economic one‐pot multicomponent reactions. Based on the results, compounds 4b and 5a demonstrated promising Glide scores and exhibited strong binding affinity with decaprenylphosphoryl‐β‐D‐ribofuranose oxidoreductase.
Mathiyazhagan Lavanya +8 more
wiley +1 more source