Results 101 to 110 of about 7,252 (218)

Organocatalytic Enantioselective Friedel-Crafts Aminoalkylation of Indoles in the Carbocyclic Ring [PDF]

, 2016
The first general catalytic method for the, so far elusive, enantioselective Friedel−Crafts functionalization of indoles in the carbocyclic ring is presented.
Blay Llinares, Gonzalo, Fernández Picot, Isabel, Montesinos Magraner, Marc, Muñoz, M. Carmen, Pedro, José Ramón, Rendón-Patiño, Alejandra, Vila Descals, Carlos   +6 more
core   +6 more sources

Doping in Organic Semiconductors: Fundamentals, Materials, and Applications

Advanced Electronic Materials, Volume 12, Issue 6, 23 March 2026.
Sergi Riera‐Galindo
wiley   +1 more source

Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents.

PLoS Neglected Tropical Diseases, 2019
New treatments are needed for neglected tropical diseases (NTDs) such as Human African trypanosomiasis (HAT), Chagas disease, and schistosomiasis. Through a whole organism high-throughput screening campaign, we previously identified 797 human kinase ...
Dana M Klug, Rosario Diaz-Gonzalez, Guiomar Pérez-Moreno, Gloria Ceballos-Pérez, Raquel García-Hernández, Veronica Gomez-Pérez, Luis Miguel Ruiz-Pérez, Domingo I Rojas-Barros, Francisco Gamarro, Dolores González-Pacanowska, María S Martínez-Martínez, Pilar Manzano, Lori Ferrins, Conor R Caffrey, Miguel Navarro, Michael P Pollastri   +15 more
doaj   +1 more source

Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors. [PDF]

J Enzyme Inhib Med Chem, 2023
Shaldam MA, Almahli H, Angeli A, Badi RM, Khaleel EF, Zain-Alabdeen AI, Elsayed ZM, Elkaeed EB, Salem R, Supuran CT, Eldehna WM, Tawfik HO.   +11 more
europepmc   +1 more source

Identification and Validation of Compounds Selectively Killing Resistant Cancer: Delineating Cell Line-Specific Effects from P-Glycoprotein-Induced Toxicity. [PDF]

, 2017
Despite significant progress, resistance to chemotherapy is still the main reason why cancer remains a deadly disease. An attractive strategy is to target the collateral sensitivity of otherwise multidrug resistant (MDR) cancer.
Cervenák, László, Füredi, András, Kucsma, Nóra, Pape, Veronika F. S., Szakács, Gergely, Szebényi, Kornélia, Tóth, Szilárd, Tóvári, József, Türk, Dóra   +8 more
core   +1 more source

Design, Synthesis and biological evaluation of novel acridine-polyamine conjugates against prostate cancer [PDF]

, 2009
Prostate cancer is the most common cause of cancer death in men, aged 85 and over. Androgen receptor, a single polypeptide with three functional domains is very important during initiation and progression of the disease.
Karodia, N, Maurice, HB, Phillips, Roger
core  

Crystal structure and Hirshfeld analysis of trans-bis(5-fluoroindoline-2,3-dione 3-oximato-κ2O2,N3)-trans-bis(pyridine-κN)copper(II)

Acta Crystallographica Section E: Crystallographic Communications, 2018
The reaction in methanol of CuII acetate monohydrate with 5-fluoroisatin 3-oxime deprotonated with KOH in a 1:2 molar ratio and recrystallization from pyridine yielded the title compound, [Cu(C8H4FN2O2)2(C5H5N)2].
Ana Paula Lopes de Melo, Leandro Bresolin, Bianca Barreto Martins, Vanessa Carratu Gervini, Adriano Bof de Oliveira   +4 more
doaj   +1 more source

Identification of sulphonamide-tethered N-((triazol-4-yl)methyl)isatin derivatives as inhibitors of SARS-CoV-2 main protease. [PDF]

J Enzyme Inhib Med Chem, 2023
ElNaggar MH, Elgazar AA, Gamal G, Hamed SM, Elsayed ZM, El-Ashrey MK, Abood A, El Hassab MA, Soliman AM, El-Domany RA, Badria FA, Supuran CT, Eldehna WM.   +12 more
europepmc   +1 more source

Facile method for the synthesis of silver nanoparticles using 3-hydrazino-isatin derivatives in aqueous methanol and their antibacterial activity

International Journal of Nanomedicine, 2014
Ayman El-Faham,1,2 Ahmed A Elzatahry,1,3 Zeid A Al-Othman,1 Elsayed Ahmed Elsayed4,5 1Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia; 2Department of Chemistry, Faculty of Science, Alexandria University, Ibrahimia,
El-Faham A, Elzatahry AA, Al-Othman ZA, Elsayed EA   +3 more
doaj  

Designing and Synthesis of New Isatin Derivatives as Potential CDK2 Inhibitors. [PDF]

Int J Mol Sci, 2022
Czeleń P, Skotnicka A, Szefler B.
europepmc   +1 more source