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Erratum: Enhanced oxidative stress response and neuroprotection of combined limb remote ischemic conditioning and atorvastatin after transient ischemic stroke in rats. [PDF]
Brain Circeuropepmc +1 more source
Remote Ischemic Per-Conditioning
Stroke, 2011 Background and Purpose— Remote ischemic preconditioning is a phenomenon by which a short period of sublethal ischemia to an organ protects against subsequent ischemia in another organ.
Cedric Manlhiot +2 more
exaly +2 more sources
Remote Ischemic Conditioning [PDF]
Journal of Cardiovascular Pharmacology and Therapeutics, 2016 This editorial describes benefits and limitations of remote ischemic conditioning. Remote ischemic conditioning was shown to reduce myocardial intact size in at least 4 sizeable clinical trials of acute myocardial infarction. It was not effective in recent studies of cardiac surgery. Reasons for these differences are discussed.
Robert A. Kloner
exaly +3 more sources
Chemical Conditioning as an Approach to Ischemic Stroke Tolerance: Mitochondria as the Target [PDF]
International Journal of Molecular Sciences, 2016 This article focuses on chemical conditioning of mitochondrial proteins as targets for neuroprotection against ischemic stroke ...
Liang-Jun Yan, Zhen Jin, Jinzi Wu
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Remote Ischemic Conditioning as an Additional Treatment for Acute Ischemic Stroke [PDF]
Stroke, 2019 Acute ischemic stroke (AIS) is the leading cause of disability in adults worldwide and has the second highest mortality of all cardiovascular diseases[1]. The burden of stroke is likely to increase significantly during the next decades, primarily due to population growth and aging[2].
Michiel C Warlé +2 more
exaly +2 more sources
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Remote Ischemic Pre-Conditioning (RIPC)
2022Ischemic pre-conditioning has been shown to protect hearts against ischemia/reperfusion (I/R)-induced cardiac injury. However, it is not feasible in clinic. Many researchers have tried to introduce brief I/R in skeletal muscle to mimic cardiac ischemic pre-conditioning, called remote ischemia pre-conditioning (RIPC).
Kyung Eun, Lee +4 more
openaire +2 more sources
Journal of Cardiovascular Medicine, 2012
Early and successful restoration of myocardial reperfusion following an ischemic event is the most effective strategy to reduce final infarct size and improve clinical outcome. However, revascularization per se may induce further myocardial damage by myocardial ischemia-reperfusion injury and worsen clinical outcome.
Schmidt, Michael R +3 more
openaire +3 more sources
Early and successful restoration of myocardial reperfusion following an ischemic event is the most effective strategy to reduce final infarct size and improve clinical outcome. However, revascularization per se may induce further myocardial damage by myocardial ischemia-reperfusion injury and worsen clinical outcome.
Schmidt, Michael R +3 more
openaire +3 more sources
The Therapeutic Potential of Ischemic Conditioning: An Update
Nature Reviews Cardiology, 2011Novel approaches are required to improve clinical outcomes in patients with coronary heart disease (CHD). Ischemic conditioning--the practice of applying brief episodes of nonlethal ischemia and reperfusion to confer protection against a sustained episode of lethal ischemia and reperfusion injury--is one potential therapeutic strategy. Importantly, the
Derek Yellon, Derek Hausenloy
exaly +3 more sources
Remote ischemic conditioning for acute ischemic stroke: dawn in the darkness
Reviews in the Neurosciences, 2016AbstractStroke is a leading cause of disability with high morbidity and mortality worldwide. Of all strokes, 87% are ischemic. The only approved treatments for acute ischemic stroke are intravenous thrombolysis with alteplase within 4.5 h and thrombectomy within 8 h after symptom onset, which can be applied to just a few patients.
Jingrui, Pan, Xiangpen, Li, Ying, Peng
openaire +2 more sources