Results 101 to 110 of about 8,004 (220)

Mitsugumin 53 Inhibits Angiogenesis Through Regulating Focal Adhesion Turnover and Tip Cell Formation

Journal of Cellular and Molecular Medicine, Volume 29, Issue 4, February 2025.
ABSTRACT Our previous studies have identified mitsugumin 53 (MG53) as a novel regulator for angiogenesis by directly entering endothelial cells and modulating focal adhesion kinase (FAK) activation, but little is known about how rhMG53 is taken up by cells and how rhMG53 mediates cell movement.
Shuangshuang Yuan, Qin Yu, Tangting Chen, Tian Li, Yongjie Li, Xin Deng, Ni Chen, Jingcan You, Rong Li, Yan Liu, Youkun Zheng, Mao Luo, Hongbin Lv, Jianbo Wu, Liqun Wang   +14 more
wiley   +1 more source

Intestinal oxygen utilisation and cellular adaptation during intestinal ischaemia–reperfusion injury

Clinical and Translational Medicine, Volume 15, Issue 1, January 2025.
During intestinal ischaemia, mitochondrial oxygen uptake is reduced when cellular oxygen partial pressure decreases to below the threshold required to maintain normal oxidative metabolism. Upon reperfusion, intestinal hypoxia may persist because microcirculatory flow remains impaired and/or because available oxygen is consumed by enzymes, intestinal ...
Paraschos Archontakis‐Barakakis, Theodoros Mavridis, David‐Dimitris Chlorogiannis, Georgios Barakakis, Eleni Laou, Daniel I. Sessler, George Gkiokas, Athanasios Chalkias   +7 more
wiley   +1 more source

Defining the organizational structure of dopamine and muscarninic acetylcholine receptors [PDF]

, 2015
No abstract ...
Alvarez-Curto, Elisa, Caltabiano, Gianluigi Caltabiano, Liste, María José Varela, Marsango, Sara, Milligan, Graeme   +4 more
core   +1 more source

Effect of Ischemic Postconditioning and Atorvastatin in the Prevention of Remote Lung Reperfusion Injury

Brazilian Journal of Cardiovascular Surgery
Objective: The aim of the present study was to evaluate the ability of ischemic postconditioning, atorvastatin and both associated to prevent or minimize reperfusion injury in the lung of rats subjected to ischemia and reperfusion by abdominal aortic ...
Carlos Henrique Marques dos Santos, Doroty Mesquita Dourado, Baldomero Antonio Kato da Silva, Henrique Budib Dorsa Pontes, Euler de Azevedo Neto, Giovanna Serra da Cruz Vendas, Ian de Oliveira Chaves, João Victor Cunha Miranda, João Victor Durães Gomes Oliva, Letícia do Espírito Santo Dias, Murillo Henrique Martins de Almeida, Trícia Luna Sampaio   +11 more
doaj   +1 more source

Putative role of ischemic postconditioning in a rat model of limb ischemia and reperfusion: involvement of hypoxia-inducible factor-1? expression

Brazilian Journal of Medical and Biological Research, 2014
Hypoxia-inducible factor-1α (HIF-1α) is one of the most potent angiogenic growth factors. It improves angiogenesis and tissue perfusion in ischemic skeletal muscle.
T. Wang, Y.T. Zhou, X.N. Chen, A.X. Zhu
doaj   +1 more source

Ischaemic post-conditioning protects lung from ischaemia-reperfusion injury by up-regulation of haeme oxygenase-1 [PDF]

, 2010
Objective: The emergence of ischaemic post-conditioning (IPO) provides a potential method for experimentally and clinically attenuating various types of organ injuries.
Ancharaz, AK, Gao, J, Liu, Kx, Luo, T, Xia, Z, Xia, Zy   +5 more
core   +1 more source

Pharmacologic pre- and postconditioning for stroke: Basic mechanisms and translational opportunity

Brain Circulation, 2015
Beyond reperfusion therapies, there are still no widely effective therapies for ischemic stroke. Although much progress has been made to define the molecular pathways involved, targeted neuroprotective strategies have often failed in clinical trials.
Elga Esposito, Rakhi Desai, Xunming Ji, Eng H Lo   +3 more
doaj   +1 more source

Ischemic Postconditioning and Milrinone [PDF]

Journal of Cardiothoracic and Vascular Anesthesia, 2018
Jochen, Steppan, Dan E, Berkowitz, Daniel, Nyhan   +2 more
openaire   +2 more sources

Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists [PDF]

, 2016
It has now been demonstrated that the μ, δ(1), δ(2), and κ(1) opioid receptor (OR) agonists represent the most promising group of opioids for the creation of drugs enhancing cardiac tolerance to the detrimental effects of ischemia/reperfusion (I/R ...
Bailey A, Cowan A, Dhawan BN, Emmerson PJ, Fryer RM, Fryer RM, Fryer RM, Genade S, Grekova TI, Gu H, Haddad GG, Hansen DD, Hess L, Hiranuma T, Huh J, Imai N, Kettler D, Khan MG, Kin H, Kiritsy‐Roy JA, Kisin I, Korobov NV., Krazinski BE, Kulbertus H, Lasukova TV, Lasukova TV, Lasukova TV, Lasukova TV, Lasukova TV, Lishmanov AYu, Lishmanov IuB, Lishmanov IuB, Lishmanov YuB, Liu X, Marson L, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Metelitsa VI, Mikhailova SD, Monassier JP., Musha T, Panova EI., Pei JM, Platonov AA, Poonyachoti S, Pugsley MK, Pyle WG, Robson P., Saeed RW, Schultz JE, Shi E, Solenkova NV, Stefano GB, Sun HT, Ugdyzhekova DS, Varga EV, Wang GY, Wong GT, Zhang Y   +64 more
core   +2 more sources

α1‐adrenergic receptor activation mimics ischemic postconditioning

The FASEB Journal, 2013
Ischemic postconditioning has been shown to reduce injury in response to ischemia/reperfusion. Because of limitations on the clinical use of ischemic postconditioning protocols, pharmacological agents that elicit a postconditioning (PostC) effect are highly desired. Previous studies have shown that stimulation of alpha1‐adrenergic receptors (α1‐ARs) is
Danielle Marie Janota, June Yun
openaire   +1 more source