Results 91 to 100 of about 8,004 (220)

Remote Ischemic Conditioning: From Bench to Bedside [PDF]

open access: yes, 2012
Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury (IRI).
Derek John Hausenloy, Shiang Yong Lim
core   +1 more source

Modelling myocardial ischemia/reperfusion injury with inflammatory response in human ventricular cardiac organoids

open access: yesCell Proliferation, Volume 58, Issue 3, March 2025.
We obtained human ventricular cardiac organoids from hiPSCs by inhibiting the retinoic acid signaling pathway in self‐organizing differentiation and co‐cultured them with monocytes under hypoxia/reoxygenation to model myocardial ischemia/reperfusion injury.
Laihai Zhang   +8 more
wiley   +1 more source

Ischemic Postconditioning Assessment in the Liver of Rats Undergoing Mesenteric Ischemia and Reperfusion

open access: yesBrazilian Journal of Cardiovascular Surgery
Introduction: Ischemic postconditioning is a method that shows evidence of efficacy in minimizing reperfusion injury; however, its effectiveness in preventing injuries in distant organs is still unknown, especially in those who have undergone mesenteric ...
Carlos Henrique Marques dos Santos   +7 more
doaj   +1 more source

Effect of postconditioning and atorvastatin in preventing remote intestinal reperfusion injury

open access: yesJournal of Coloproctology, 2017
Objective: To evaluate the capacity of ischemic postconditioning and atorvastatin in prevent or minimize reperfusion injury in small bowel of rats subjected to ischemia and reperfusion by abdominal aorta clamping.
Carlos Henrique Marques dos Santos   +7 more
doaj   +1 more source

Immediate remote ischemic postconditioning after hypoxia ischemia in piglets protects cerebral white matter but not grey matter [PDF]

open access: yes, 2015
Remote ischemic postconditioning (RIPostC) is a promising therapeutic intervention whereby brief episodes of ischemia/reperfusion of one organ (limb) mitigate damage in another organ (brain) that has experienced severe hypoxia-ischemia.
Alonso-Alconada, Daniel   +19 more
core   +2 more sources

m6A Ribonucleic Acid Methylation in Fibrotic Diseases of Visceral Organs

open access: yesSmall Science, Volume 5, Issue 2, February 2025.
This review provides a systematic overview of recent studies on m6A modification in fibrotic diseases affecting visceral organs, including the lungs, heart, liver, and kidneys. Furthermore, it emphasizes the significant advancements in understanding how m6A methylation of ribonucleic acid influences fibrosis in these organs and explores potential ...
Xiaoniu Dai   +7 more
wiley   +1 more source

HIF-1α mediates isoflurane-induced vascular protection in subarachnoid hemorrhage [PDF]

open access: yes, 2015
OBJECTIVE: Outcome after aneurysmal subarachnoid hemorrhage (SAH) depends critically on delayed cerebral ischemia (DCI) – a process driven primarily by vascular events including cerebral vasospasm, microvessel thrombosis, and microvascular dysfunction ...
Gidday, Jeffrey M   +6 more
core   +3 more sources

Hypoxic Postconditioning Offers Neuroprotection Against Transient Cerebral Ischemia via Down‐Regulation of rno_piR_011022

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.
The expression profiles of piRNAs in CA1 were significantly changed after tGCI. HPC down‐regulated the expressions of the top 5 piRNAs associated with synaptic function, including rno_piR_000618, rno_piR_009428, rno_piR_017990, rno_piR_014971, and rno_piR_011022 induced by tGCI.
Meiyan Chen   +6 more
wiley   +1 more source

Fetal and neonatal brain protection at term—The role of translational experimental models

open access: yes
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 1, Page 4-6, January 2026.
Juulia Lantto   +2 more
wiley   +1 more source

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