Results 21 to 30 of about 11,357 (181)

Effects of ischemia and omeprazole preconditioning on functional recovery of isolated rat heart

Brazilian Journal of Cardiovascular Surgery, 2015
Objective:The aim of this study was to compare protective effects of ischemic and potential protective effects of pharmacological preconditioning with omeprazole on isolated rat heart subjected to ischemia/reperfusion.Methods:The hearts of male Wistar ...
Nevena Jeremic, Anica Petkovic, Ivan Srejovic, Vladimir Zivkovic, Dragan Djuric, Vladimir Jakovljevic   +5 more
doaj   +1 more source

The tole of ischemic preconditioning in acute myocardial infarction

Medicinski pregled, 2005
Introduction Ischemic preconditioning is a phenomenon in which brief episodes of ischemia and reperfusion increase myocardial tolerance and substantially reduce the infarction size. Case report Two patients with acute left anterior descending artery occlusion received fibrinolytic therapy within 6 hours of symptom onset, but nevertheless developed ...
Andelka, Ristić, Milorad, Damjanović, Branislav, Baskot, Sasa, Rafaelovski   +3 more
openaire   +3 more sources

Impact of hypoglycemic agents on myocardial ischemic preconditioning

World Journal of Diabetes, 2014
Murry et al in 1986 discovered the intrinsic mechanism of profound protection called ischemic preconditioning. The complex cellular signaling cascades underlying this phenomenon remain controversial and are only partially understood. However, evidence suggests that adenosine, released during the initial ischemic insult, activates a variety of G protein-
Rosa Maria, Rahmi Garcia, Paulo Cury, Rezende, Whady, Hueb   +2 more
openaire   +2 more sources

Role of microtubules in ischemic preconditioning against myocardial infarction [PDF]

Cardiovascular Research, 2004
The role of microtubules in ischemic preconditioning (PC) was investigated in isolated perfused rabbit hearts.Myocardial infarction was induced by 30-min global ischemia and 2-h reperfusion, and infarct size was expressed as a percentage of the left ventricle (%IS/LV).
Yuichi, Nakamura, Tetsuji, Miura, Atsushi, Nakano, Yoshihiko, Ichikawa, Toshiyuki, Yano, Hironori, Kobayashi, Yoshihiro, Ikeda, Takayuki, Miki, Kazuaki, Shimamoto   +8 more
openaire   +2 more sources

Is Local Nitric Oxide Availability Responsible for Myocardial Salvage after Remote Preconditioning?

Arquivos Brasileiros de Cardiologia, 2016
Background: Remote ischemic preconditioning (RIPC) represents an attractive therapy for myocardial protection, particularly when ischemic events can be anticipated. Although several hypothetic mechanisms have been proposed, no definite molecular pathways
Esbeidira Aranet Arroyo-Martínez, Alejandra Meaney, Gabriela Gutiérrez-Salmeán, Juan Miguel Rivera-Capello, Vidal González-Coronado, Alejandro Alcocer-Chauvet, Genaro Castillo, Nayelli Nájera, Guillermo Ceballos, Eduardo Meaney   +9 more
doaj   +1 more source

The impact of a single episode of remote ischemic preconditioning on myocardial injury after elective percutaneous coronary intervention

Advances in Interventional Cardiology, 2017
Introduction : Myocardial injury after percutaneous coronary intervention (PCI) occurs in approximately 30% of procedures, and is related to worse prognosis.
Mustafa A. Yılmaztepe, Gökay Taylan, Meryem Aktoz, Hanefi Y. Gürlertop, Yüksel Aksoy, Fatih Özçelik, Kenan Yalta, Galip Ekuklu   +7 more
doaj   +1 more source

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

Cardiac Remote Conditioning and Clinical Relevance: All Together Now!

Engineering, 2015
Acute myocardial infarction (AMI) is the leading cause of death and disability worldwide. Timely reperfusion is the standard of care and results in decreased infarct size, improving patient survival and prognosis.
Kristin Luther, Yang Song, Yang Wang, Xiaoping Ren, W. Keith Jones   +4 more
doaj   +1 more source

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

iNew Medicine, EarlyView.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng, Wenhui Zhao, Min Wang, Xianwen Wang   +3 more
wiley   +1 more source

Extracellular Adenosine Formation by Ecto-5'-Nucleotidase (CD73) Is No Essential Trigger for Early Phase Ischemic Preconditioning. [PDF]

PLoS ONE, 2015
Adenosine is a powerful trigger for ischemic preconditioning (IPC). Myocardial ischemia induces intracellular and extracellular ATP degradation to adenosine, which then activates adenosine receptors and elicits cardioprotection.
Georg Wolff, Richard Truse, Ulrich Decking   +2 more
doaj   +1 more source