Results 161 to 170 of about 865,811 (229)

Circadian-Dependent Intermittent Fasting Influences Ischemic Tolerance and Dendritic Spine Remodeling. [PDF]

Stroke
Jeong S, Chokkalla AK, Davis CK, Jeong H, Chelluboina B, Arruri V, Kim B, Narman A, Bathula S, Arumugam TV, Bendlin BB, Vemuganti R.   +11 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Inhibition of SCF^KDM2A/USP22-dependent nuclear β-catenin ubiquitylation mediates cerebral ischemic tolerance. [PDF]

Commun Biol
Zuo Y, Xue J, Wen H, Zhan L, Chen M, Sun W, Xu E.   +6 more
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Nitrates In Ischemic Preconditioning

, 2017
Ischemic preconditioning is the innate ability of the heart to protect itself from an ischemic episode that can otherwise lead to a myocardial infarct.
NasserEddin, Ibrahim
core  

Preconditioning-Induced Facilitation of Lactate Release from Astrocytes Is Essential for Brain Ischemic Tolerance. [PDF]

eNeuro
Hirayama Y, Le HPN, Hashimoto H, Ishii I, Koizumi S, Anzai N.   +5 more
europepmc   +1 more source

Integrative transcriptomic and metabolic analyses of the mammalian hibernating brain identifies a key role for succinate dehydrogenase in ischemic tolerance

, 2023
Bernstock JD, Willis CM, Garcia-Segura ME, Gaude E, Anni D, Lee Y, Thomas LW, Casey A, Vicario N, Leonardi T, Nicaise AM, Gessler FA, Izzy S, Buffelli MR, Seidlitz J, Srinivasan S, Murphy MP, Ashcroft M, Cambiaghi M, Hallenbeck JM, Peruzzotti-Jametti L.   +20 more
europepmc   +1 more source

Coronary Flow in Hypertrophic Obstructive Cardiomyopathy—Immediate Effects of Alcohol Septal Ablation

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Hypertrophic cardiomyopathy is associated with alterations in coronary microvascular function which have variable pathophysiologic mechanisms, and variable reversibility acutely and chronically following alcohol septal ablation (ASA).
Vojko V. Misevic, Ana N. Golocevac, Kosta S. Krupnikovic, Stefan B. Timcic, Natalija B. Arnautovic, Dragana D. Radoicic, Milan R. Dobric, Aleksandar D. Mandic, Stefan S. Zivkovic, Aleksa D. Obradovic, Vladimir D. Mihajlovic, Natalija R. Odanovic, Ivan S. Ilic   +12 more
wiley   +1 more source

A20 negatively regulates necroptosis-induced microglia/macrophages polarization and mediates cerebral ischemic tolerance via inhibiting the ubiquitination of RIP3. [PDF]

Cell Death Dis
Qiu M, Zhang W, Dai J, Sun W, Lai M, Tang S, Xu E, Ning Y, Zhan L.   +8 more
europepmc   +1 more source