Transcriptome-wide dynamics of m6A methylation in ISKNV and Siniperca chuatsi cells infected with ISKNV [PDF]
BMC GenomicsInfectious spleen and kidney necrosis virus (ISKNV) is a highly virulent and rapidly transmissible fish virus that poses threats to the aquaculture of a wide variety of freshwater and marine fish.
Qijin Miao +9 more
doaj +3 more sources
Hypermethylated genome of a fish vertebrate iridovirus ISKNV plays important roles in viral infection [PDF]
Communications BiologyIridoviruses are nucleocytoplasmic large dsDNA viruses that infect invertebrates and ectothermic vertebrates. The hypermethylated genome of vertebrate iridoviruses is unique among animal viruses.
Mincong Liang +8 more
doaj +4 more sources
Investigating the mechanism of heat-shock protection in ISKNV-infected tilapia brain cell line [PDF]
Microbiology SpectrumInfectious spleen and kidney necrosis virus (ISKNV) is the causative agent of a fatal disease in many fish species, resulting in mass mortalities and significant economic losses.
Angela Naa Amerley Ayiku +5 more
doaj +4 more sources
Heliyon, 2023 Infectious Spleen and Kidney Necrosis Virus (ISKNV) is linked to severe infections that cause significant financial losses in global aquaculture. ISKNV enters the host cell through its major capsid protein (MCP), and the resulting infection can lead to ...
Nasim Habib +2 more
exaly +5 more sources
First report of infectious spleen and kidney necrosis virus (ISKNV) in two native cichlids cultured in Brazil [PDF]
Semina: Ciências AgráriasPeacock bass (syn.: tucunaré, Cichla ocellaris) and the pearl cichlids (syn.: acará, Geophagus brasiliensis) are South American cichlids that are highly valued in both the ornamental and sport fish industries.
Ulisses de Pádua Pereira +9 more
doaj +4 more sources
Development of a gene-deleted live attenuated candidate vaccine against fish virus (ISKNV) with low pathogenicity and high protection [PDF]
iScience, 2021 Summary: Aquaculture provides important food, nutrition, and income sources for humans. However, aquaculture industry is seriously threatened by viral diseases.
Ruoyun Zeng +8 more
doaj +3 more sources
The viral TRAF protein (ORF111L) from infectious spleen and kidney necrosis virus interacts with TRADD and induces caspase 8-mediated apoptosis. [PDF]
PLoS ONE, 2012 Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the Megalocytivirus genus of the Iridoviridae family. It causes a serious and potentially pandemic disease in wild and cultured fishes.
Bai-Liang He +6 more
doaj +4 more sources
Development of Duplex Loop-Mediated Isothermal Amplification with Hydroxynaphthol Blue for Detection of Infectious Spleen and Kidney Necrosis Virus and Aeromonas hydrophila in Chinese Perch (Siniperca chuatsi) [PDF]
MicroorganismsBacterial sepsis caused by Aeromonas hydrophila (A. hydrophila) and infectious spleen and kidney necrosis virus disease (ISKNVD) caused by infectious spleen and kidney necrosis virus (ISKNV) frequently result in significant mortality among Chinese perch (
Xiao He +5 more
doaj +2 more sources
Development of a Double-Antibody Sandwich ELISA for Rapid Detection of the MCP Antigen Concentration in Inactivated ISKNV Vaccines [PDF]
Vaccines, 2021 Infectious spleen and kidney necrosis virus (ISKNV) resulted in severe systemic diseases with high morbidity and mortality in Siniperca chuatsi. Vaccination is the primary method for effective prevention and control of these diseases.
Hongru Liang +8 more
doaj +3 more sources
Rapid, sensitive, and visual detection of mandarin fish ranavirus and infectious spleen and kidney necrosis virus using an RPA-CRISPR/Cas12a system [PDF]
Frontiers in MicrobiologyIridoviruses are large cytoplasmic icosahedral viruses that contain dsDNA. Among them, mandarin fish ranavirus (MRV) and infectious spleen and kidney necrosis virus (ISKNV) are particularly notable due to their high contagiousness and pathogenicity ...
Zhoutao Lu +6 more
doaj +2 more sources