Metabolites, 2019 Infectious spleen and kidney necrosis virus (ISKNV) has caused serious economic losses in the cultured mandarin fish (Siniperca chuatsi) industry in China.
Xiaozhe Fu, Yinjie Niu, Ningqiu Li
exaly +3 more sources
scTRIM44 Positively Regulated Siniperca Chuatsi Rhabdovirus Through RIG-I- and MDA5-Mediated Interferon Signaling [PDF]
VirusesTripartite Motif-Containing 44 (TRIM44) is responsible for cancers, neurodegenerative diseases, and viral infections. However, the role of Siniperca chuatsi TRIM44 (scTRIM44) during viral infection remains unclear.
Yinjie Niu +7 more
doaj +2 more sources
In field use of water samples for genomic surveillance of infectious spleen and kidney necrosis virus (ISKNV) infecting tilapia fish in Lake Volta, Ghana [PDF]
PeerJViral outbreaks are a constant threat to aquaculture, limiting production for better global food security. A lack of diagnostic testing and monitoring in resource-limited areas hinders the capacity to respond rapidly to disease outbreaks and to prevent ...
Shayma Alathari +10 more
doaj +3 more sources
Multiplex polymerase chain reaction (PCR) with Nanopore sequencing for sequence-based detection of four tilapia pathogens [PDF]
PeerJBackground Tilapia aquaculture faces significant threats posed by four prominent pathogens: tilapia lake virus (TiLV), infectious spleen and kidney necrosis virus (ISKNV), Francisella orientalis, and Streptococcus agalactiae.
Jérôme Delamare-Deboutteville +7 more
doaj +3 more sources
ISKNV Triggers AMPK/mTOR-Mediated Autophagy Signaling through Oxidative Stress, Inducing Antioxidant Enzyme Expression and Enhancing Viral Replication in GF-1 Cells [PDF]
VirusesInfectious spleen and kidney necrosis virus (ISKNV) infections can induce the process of host cellular autophagy but have rarely been identified within the molecular autophagy signaling pathway.
Tsai-Ching Hsueh +2 more
doaj +2 more sources
Evaluation of a Low-Temperature Immersion Immunization Strategy for the Infectious Spleen and Kidney Necrosis Virus orf037l Gene-Deleted Attenuated Vaccine [PDF]
VaccinesBackground: Infectious spleen and kidney necrosis virus (ISKNV) poses a significant threat to aquaculture sustainability, particularly affecting mandarin fish (Siniperca chuatsi) and causing significant economic losses. Methods: To address this challenge,
Weiqiang Pan +9 more
doaj +2 more sources
Mandarin fish tankyrase 1-like protein regulates the Wnt/β-catenin pathway and facilitates the infectious spleen and kidney necrosis virus replication [PDF]
Comparative Immunology ReportsTankyrase (TNKS), a poly (ADP-ribose) polymerase (PARP) protein, mediates the PARylation of substrates, ultimately guiding them towards proteasome-dependent degradation or altering their localization.
Zhimin Li +6 more
doaj +2 more sources
The Stability and Efficency of CPB Cells Were Acclimated for Virus Proliferation [PDF]
VaccinesBackground: Vaccinations are still the most effective means of preventing and controlling fish viral diseases, and cells are an important substrate for the production of a viral vaccine.
Yinjie Niu +7 more
doaj +2 more sources
The Role of Gut Microbiota in Fish Viral Infection: Mechanisms and Microbiota-Targeted Interventions. [PDF]
Aquac NutrViral diseases represent one of the major threats to the global aquaculture industry. In recent years, the relationship between gut microbiota and viral infections in fish has garnered increasing attention. The gut microbiota contributes critically to fish health and is involved in antiviral defense through immune regulation, secretion of microbial ...
Zhao Q, Shao J, Chen Y, Zhang H.
europepmc +2 more sources
Viruses, 2012 The genus Megalocytivirus, represented by red sea bream iridovirus (RSIV), the first identified and one of the best characterized megalocytiviruses, Infectious spleen and kidney necrosis virus (ISKNV), the type species of the genus, and numerous other ...
Kazuhiro Nakajima, Jun Kurita
doaj +4 more sources