Results 111 to 120 of about 126,560 (317)
Biotechnology and Bioengineering, EarlyView.ABSTRACT Clinical islet transplantation has long been investigated as a potential cure for type 1 diabetes (T1D), yet standard intrahepatic delivery leaves islets prone to an instant blood‐mediated inflammatory response. Herein, we investigated the design of microporous poly(D,l‐lactide‐co‐glycolide) (PLG) scaffolds for extrahepatic islet ...
Jessica L. King +15 more
wiley +1 more source
Hypertonicity during a rapid rise in D-glucose mediates first-phase insulin secretion
Frontiers in EndocrinologyIntroductionBiphasic insulin secretion is an intrinsic characteristic of the pancreatic islet and has clinical relevance due to the loss of first-phase in patients with Type 2 diabetes.
Varun Kamat, Ian R. Sweet
doaj +1 more source
Evaluating Isochoric Freezing as a Strategy for Storage of Red Blood Cells
Biotechnology and Bioengineering, EarlyView.ABSTRACT Red blood cells (RBCs) are needed for life‐saving blood transfusions, but they undergo continuous degradation during storage. Preserving RBCs for clinical transfusion remains a challenge due to storage‐induced damage and limitations of traditional freezing methods.
Yuanheng Zhao +3 more
wiley +1 more source
Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond
BMEMat, EarlyView.Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad +8 more
wiley +1 more source
Biological Reviews, EarlyView.ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito +2 more
wiley +1 more source
Early evolutionary history of the seed
Biological Reviews, EarlyView.ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman +2 more
wiley +1 more source
Editorial: Look who’s talking: Dialogues with beta cells
Frontiers in Endocrinology, 2023 Noèlia Téllez +5 more
doaj +1 more source
Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation [PDF]
, 2016 S. E. Cross +14 more
openalex +1 more source