Results 121 to 130 of about 47,870 (244)

Long‐distance pollen transport mediated by migratory hoverflies

Ecography, EarlyView.
Long‐distance animal migrations shape ecosystems by redistributing nutrients, connecting populations, and mediating ecological interactions. However, the ecological contributions of many abundant insect migrants remain poorly quantified. Hoverflies are among the most numerous migratory insects and highly efficient pollinators, suggesting that their ...
Antonín Hlaváček, Martin Freudenfeld, Tadeáš Ryšan, Šimon Zeman, Vojtěch Jirásek, Radek K. Lučan, Karl R. Wotton, Jakub Štenc, Jiří Hadrava   +8 more
wiley   +1 more source

Hypertonicity during a rapid rise in D-glucose mediates first-phase insulin secretion

Frontiers in Endocrinology
IntroductionBiphasic insulin secretion is an intrinsic characteristic of the pancreatic islet and has clinical relevance due to the loss of first-phase in patients with Type 2 diabetes.
Varun Kamat, Ian R. Sweet
doaj   +1 more source

Islet organoids: a new hope for islet transplantation in diabetes

Frontiers in Immunology
Diabetes mellitus, including Type 1 diabetes (T1D) and advanced Type 2 diabetes (T2D), remains a major global health challenge due to the destruction or dysfunction of insulin-producing β-cells. Islet transplantation offers a promising therapeutic strategy. However, it is limited by organ shortage globally and other risk factors. Recent advancements in
Xuemei Yu, Chengkong Liu, Zheng Kuang, Siyuan Song, Limin Tian, Yi Wang, Yi Wang   +6 more
openaire   +3 more sources

Effect of Triple Costimulation Blockade on Islet Allograft Survival in Sensitized Mice

, 2010
Background. Islet allograft rejection in sensitized recipients is difficult to control by costimulation blockade using anti-CD154 and cytotoxic T-lymphocyte antigen-4 immunoglobulin (CTLA4Ig).
M. Kumagai-Braesch, A. Tibell, T. Iwata, J. Holgersson, Iwata, T., Diab, R., Ekberg, Henrik, R. Diab, Kumagai-Braesch, M., Corbascio, M., M. Corbascio, H. Ekberg, Tibell, A., Holgersson, J.   +13 more
core   +1 more source

Unraveling the Interplay Between Collaborative Governance and Experimentation for Transformative Potential in Circular Water Systems: A Dutch Case Study

Environmental Policy and Governance, EarlyView.
ABSTRACT Freshwater availability is a critical climate change challenge in coastal delta regions. This challenge requires a transformative change toward circular water management. While experimentation and collaborative governance are recognized as enablers of transformative change, their interaction remains complex and insufficiently understood ...
Flavia Simona Albu Cosoveanu, Kirsty Holstead, Jean‐Marie Buijs, Dave Huitema   +3 more
wiley   +1 more source

Autologous islet transplantation: systematic review of the literature and first case report at University of Padova. [PDF]

openCONTESTO La pancreasectomia totale con autotrapianto di insule pancreatiche (TPIAT) è un’opzione terapeutica consolidata ed efficace per i pazienti con pancreatite cronica intrattabile.
QUARATINO, BENEDETTA
core  

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee, Rachel C. Hector, Lynn Pezzanite, Eric Gilleland, Marlis L. Rezende   +4 more
wiley   +1 more source

Screening and identification of novel peptides stimulating GLP‐1 secretion from plant proteins after simulated gastrointestinal digestion

Food Biomacromolecules, EarlyView.
Effects of digestive products of quinoa, oat, barley, and mungbean proteins on GLP‐1 secretion are investigated using STC‐1 cell and animal experiments, and novel GLP‐1 secretion‐stimulating peptides are successfully identified by column chromatography and LC–MS/MS.
Hongdong Song, Shaoxia Ren, Qiuyun Fu, Lei Xue, Kai Huang, Hongwei Cao, Zetang Zhang, Junhu Li, Xiao Guan   +8 more
wiley   +1 more source

A Small-Molecule Mitofusin 1 Agonist Enhances Islet Survival Under Hypoxic Conditions In Vitro and Improves Transplantation Outcomes

Biomolecules
Background: Hypoxia-induced oxidative stress compromises the survival and function of transplanted islets, contributing to high rates of islet transplantation failure.
Yue Wang, Bofeng Yang, Pengkun Song, Zexiang Ji, Di Zhang, Wenxuan Chen, Lei Du, Lei Liu   +7 more
doaj   +1 more source