Results 141 to 150 of about 192,930 (304)
iNew Medicine, EarlyView.ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
iNew Medicine, EarlyView.The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
Is it currently possible to evaluate the risk posed by PERVs for clinical xenotransplantation? [PDF]
, 2018 Denner, Joachim +2 more
core +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.Identifying novel treatments for diabetic management is always a competitive research topic all over the world. PPAR‐γ is one of the key regulators involved in glucose and lipid metabolism and improves insulin sensitivity and glucose homeostasis. This study investigated the impacts of 639 traditional Chinese medicine (TCM) on PPAR‐γ gene promoter ...
Mingyuan Dou +9 more
wiley +1 more source
Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder
JCPP Advances, EarlyView.Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista +5 more
wiley +1 more source
A Practical Guide to Rodent Islet Isolation and Assessment
Biological Procedures Online, 2009 Pancreatic islets of Langerhans secrete hormones that are vital to the regulation of blood glucose and are, therefore, a key focus of diabetes research. Purifying viable and functional islets from the pancreas for study is an intricate process.
Carter Jeffrey +4 more
doaj
JCPP Advances, EarlyView.Abstract Background We conducted a systematic review and meta‐analysis to examine the effects of mindfulness‐based interventions (MBIs) on emotion regulation (ER) and emotion dysregulation (ED) in people with any mental health condition. Methods Following a pre‐registered protocol (PROSPERO CRD42024618605), we searched multiple databases (Web of ...
Thomas Easdale‐Cheele +4 more
wiley +1 more source
Spatiotemporal Changes in Precipitation Concentration in the Atlantic‐European Region
International Journal of Climatology, EarlyView.This study analyses changes in precipitation concentration using ERA5 and E‐OBS datasets. Gini index as a measure of precipitation concentration revealed a gradual expansion of areas with increasing unevenness in precipitation distribution across the Atlantic‐European region since 1961.
Petr Dobrovolný +4 more
wiley +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract BACKGROUND Shrimp is among the most perishable seafood commodities, and its freshness is still largely assessed through time‐consuming laboratory methods. pH‐responsive colorimetric films have received growing attention as they allow visual, real‐time quality monitoring without specialized equipment.
Tuncay Gümüş +2 more
wiley +1 more source