Results 71 to 80 of about 21,364 (194)
From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system
The FEBS Journal, EarlyView.The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger +3 more
wiley +1 more source
Genes, fish and fisheries: translating science into policy
Journal of Fish Biology, EarlyView.Abstract The 2024 Annual Symposium of the Fisheries Society of the British Isles reviewed the burgeoning impact of ‘omics’ technologies on fish ecology, management and forecasting. As with life sciences more generally, major advances in speed, cost‐effectiveness and breadth of applications in ‘omics’ has had profound societal and environmental impacts.
Gary R. Carvalho
wiley +1 more source
Implication of Mitochondrial Cytoprotection in Human Islet Isolation and Transplantation
Biochemistry Research International, 2012 Islet transplantation is a promising therapy for type 1 diabetes mellitus; however, success rates in achieving both short- and long-term insulin independence are not consistent, due in part to inconsistent islet quality and quantity caused by the complex
Yong Wang +9 more
doaj +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Isolating Human Islets of Langerhans Causes Loss of Decay Accelerating Factor (CD55) on β-Cells
Cell Transplantation, 2008 It has previously been reported that human decay accelerating factor (DAF; CD55) is not expressed on cells isolated from human islets. We have investigated if this absence is caused by the islet isolation procedure and/or the single cell isolation ...
Joo Ho Tai +5 more
doaj +1 more source
Periodontology 2000, EarlyView.Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi +4 more
wiley +1 more source
Understanding exosomes in diabetic wound healing
Periodontology 2000, EarlyView.Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad +4 more
wiley +1 more source
A Model for Human Islet Transplantation to Immunodeficient Streptozotocin-Induced Diabetic Mice
Cell Transplantation, 2018 Streptozotocin (STZ) is a cytotoxic glucose analogue that causes beta cell death and is widely used to induce experimental diabetes in rodents. The sensitivity of beta cells to STZ is species-specific and human beta cells are resistant to STZ.
Elisabet Estil·les +3 more
doaj +1 more source
Pancreas and islet transplantation
Journal of British Surgery, 1998 77804
White, SA, London, NJM
openaire +3 more sources
Regulated Cell Death Seen through the Lens of Islet Transplantation
Cell Transplantation, 2018 Clinical islet transplantation effectively restores euglycemia and corrects glycosylated hemoglobin in labile type 1 diabetes mellitus (T1DM). Despite marked improvements in islet transplantation outcomes, acute islet cell death remains a substantial ...
Antonio Bruni +3 more
doaj +1 more source