Potential benefits and risks of clinical xenotransplantation [PDF]
The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
core +2 more sources
Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck +4 more
wiley +1 more source
Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller +5 more
wiley +1 more source
Modeling of reaction-diffusion transport into a core-shell geometry [PDF]
Fickian diffusion into a core-shell geometry is modeled. The interior core mimics pancreatic Langerhan islets and the exterior shell acts as inert protection.
Beckman, S. +5 more
core +3 more sources
Coxsackie-adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes [PDF]
Objectives: One of the theories connecting enterovirus (EV) infection of human islets with type 1 diabetes (T1D) is the development of a fertile field in the islets.
Alhazmi, A +69 more
core +1 more source
Fusion of secretory vesicles isolated from rat liver [PDF]
Secretory vesicles isolated from rat liver were found to fuse after exposure to Ca2+. Vescle fusion is characterized by the occurrence of twinned vesicles with a continuous cleavage plane between two vesicles in freeze-fracture electron microscopy.
A. Amsterdam +75 more
core +1 more source
Antidiabetic effects of fennel leaf aqueous extract in alloxan-induced diabetic rats
Background Diabetes Mellitus is a common chronic metabolic disease in the world population. There is evidences on the anti-hyperglycemic effects of different parts of fennel; however, the reports about antidiabetic activity of fennel leaves are not ...
Mahdi Noureddini +5 more
doaj +1 more source
Prediction of Pancreatic Islet Yield After Pancreatectomy Using Optical Coherence Elastography
Intraoperative assessment of pancreatic quality, followed by sampling for the potential isolation of Langerhans islets for subsequent autotransplantation, is currently a key component of post-total pancreatectomy diabetes mellitus treatment.
Ekaterina Gubarkova +11 more
doaj +1 more source
System-L amino acid transporters play a key role in pancreatic b-cell signalling and function [PDF]
The branched-chain amino acids (BCAA) leucine, isoleucine and valine, are essential amino acids that play a critical role in cellular signalling and metabolism.
Alan Bevington +7 more
core +1 more source

