Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells. [PDF]
, 2016 Glucagon is one of the main regulators of blood glucose levels and dysfunctional stimulus secretion coupling in pancreatic A-cells is believed to be an important factor during development of diabetes.
Ahlstedt, I. +3 more
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Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding
Molecular Metabolism, 2022 Objective: Identifying the transcripts which mediate genetic association signals for type 2 diabetes (T2D) is critical to understand disease mechanisms. Studies in pancreatic islets support the transcription factor ZMIZ1 as a transcript underlying a T2D ...
Tamadher A. Alghamdi +13 more
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Advanced Biomedical Research, 2015 Background: Tissue transplantation plays a pivotal role in the treatment of diseases. Pancreatic beta cell transplantation is the best way to obtain normal blood glucose in patients with diabetes type 1.
Rostam Ghorbani +3 more
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Geometric and topological characterization of the cytoarchitecture of islets of Langerhans. [PDF]
PLoS Comput Biol, 2023 Aggarwal M +3 more
europepmc +1 more source
Histology and immunofluorescent study of the pancreas in lovebird (Agapornis personatus)
Veterinary Medicine and ScienceBackground Lovebird (Agapornis personatus) is a monotypic species of bird of the lovebird genus in the parrot family Psittaculidae and order Psittaciformes.
Nader Goodarzi, Ayda Bashiri
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CHANGES IN THE ISLETS OF LANGERHANS IN PREGNANCY AND IN OTHER CONDITIONS [PDF]
, 1933 William Cramer
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Arquivos de Gastroenterologia, 2005 RACIONAL: A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina, mantendo os níveis glicêmicos dentro da normalidade.
Eleazar Chaib +3 more
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Adenoma of Islets of Langerhans Associated with Hypoglycaemia [PDF]
, 1933 R. Cairns, Samuel Tanner
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Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. [PDF]
, 1995 Insulin-dependent diabetes mellitus (IDDM) is thought to be an immunologically mediated disease resulting in the complete destruction of the insulin-producing islets of Langerhans.
Bluestone, JA +7 more
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Expression of neurogenin3 reveals an islet cell precursor population in the pancreas [PDF]
, 2000 Differentiation of early gut endoderm cells into the endocrine cells forming the pancreatic islets of Langerhans depends on a cascade of gene activation events controlled by transcription factors including the basic helix-loop-helix (bHLH) proteins.
Anderson, David J. +8 more
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