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Semaphorin 3G regulates sympathetic nerve innervations of islet of Langerhans
, 2013 俊一郎 大西
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Paracrine Interactions Within Islets of Langerhans
Journal of Molecular Neuroscience, 2012Glucose supply fluctuates between meal and fasting periods and its consumption by the body varies greatly depending on bodily metabolism. Pancreatic islets of Langerhans secrete various endocrine hormones including insulin and glucagon to keep blood glucose level relatively constant.
D. Koh, Jung-Hwa Cho, Liangyi Chen
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Cryopreservation of islets of Langerhans
Cryobiology, 1981Abstract Development of techniques for cryopreservation of pancreatic islets of Langerhans could potentially allow for increased freedom from the time restrictions presently affecting viability in islet cell transplantation. While several investigators have attempted islet cell freezing and have obtained favorable in vitro results after thawing ...
L H, Toledo-Pereyra +2 more
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3D Bioprinting of Functional Islets of Langerhans in an Alginate/Methylcellulose Hydrogel Blend
Advanced Healthcare Materials, 2019Transplantation of pancreatic islets is a promising strategy to alleviate the unstable blood‐glucose control that some patients with diabetes type 1 exhibit and has seen many advances over the years.
S. Duin +6 more
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Pancreatic Blood Flow with Special Emphasis on Blood Perfusion of the Islets of Langerhans.
Comprehensive Physiology, 2019The pancreatic islets are more richly vascularized than the exocrine pancreas, and possess a 5- to 10-fold higher basal and stimulated blood flow, which is separately regulated.
L. Jansson, P. Carlsson
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Vitrification of human islets of Langerhans
Cryobiology, 1987Cryopreservation of human islets of Langerhans by vitrification was studied. Isolated islets were divided into four groups: (1) control islets which were cultured for 6 days, (2) islets which were vitrified after 2 days of culture, (3) control islets which were cultured for 10-13 days, and (4) islets which were vitrified after 6-9 days of culture ...
N H, Jutte +4 more
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Multiple Transplantations of Islets of Langerhans
European Surgical Research, 1977In 6 diabetic rats about 1,000 isolated islets of Langerhans were transplanted into the liver with little effect on the uninsulinism and hyperglycemia. Subsequently, a second transplantation resulted in a decrease of blood sugar to normal and in a reversal of the loss in body weight. Finally, in animals who had reversed to diabetes again, a third islet
K D, Rumpf, D, Löhlein, , Pichlmayr
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Glucoreceptor Mechanisms in Islets of Langerhans
Diabetes, 1972A widely accepted concept has been that metabolites of glucose or factors associated with glucose metabolism, rather than glucose itself, trigger insulin release from the β cells. If this concept is correct, levels of metabolites or cofactors or of both should change within seconds of the glucose pulse.
F M, Matschinsky +3 more
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GABA production in rat islets of Langerhans
Diabetes, 1993Homogenates of pancreatic islets catalyzed breakdown of L-glutamate to GABA with a rate of 0.24 ± 0.04 nmol · min−1 · mg−1 protein at 37°C. The formation of GABA was stimulated by addition of pyridoxal phosphate in the range 0.05–1 microM (0.97 ± 0.02 nmol · min−1 · mg protein-1 at a saturating cofactor concentration), which indicates that the process ...
M, Michalik, J, Nelson, M, Erecińska
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