In vitro characterization of rare anti-αIIbβ3 isoantibodies produced by patients with Glanzmann thrombasthenia that severely block fibrinogen binding and generate procoagulant platelets via complement activation [PDF]
Glanzmann thrombasthenia (GT) is a rare bleeding disorder caused by inherited defects of the platelet αβ integrin. Platelet transfusions can be followed by an immune response that can block integrin function by interfering with fibrinogen binding.
Christine S.M. Lee+7 more
europepmc +6 more sources
Evidence for an influence of secretor status on levels of the ABO-isoantibodies in serum
SanmukhR Joshi+2 more
exaly +4 more sources
QUANTITATIVE STUDIES OF THE SENSITIVITY OF NORMAL AND NEOPLASTIC MOUSE CELLS TO THE CYTOTOXIC ACTION OF ISOANTIBODIES [PDF]
Experiments were performed to study the mechanisms of the sensitivity of normal and neoplastic mouse cells to the cytotoxic action of humoral isoantibodies. A quantitative in vitro absorption procedure was used to compare the residua] hemagglutinin titer
Erna Möller, Göran Möller
openalex +4 more sources
Prevalence of a Novel Immunogenic Feline Erythrocyte Antigen (FEA 6) and Expression Patterns Between FEAs [PDF]
ABSTRACT Background After the identification of five novel feline erythrocyte antigens (FEAs) and evidence establishing FEA 1's immunogenicity, attempts to sensitize a cat to FEA 4 unexpectedly resulted in the production of alloantibodies directed against an unknown antigen, named FEA 6.
Félix Bajon+2 more
wiley +2 more sources
THE PRODUCTION OF ISOANTIBODIES IN THE DOG BY IMMUNIZATION WITH HOMOLOGOUS TISSUE
Kasakura S+4 more
openaire +4 more sources
Association of the blood groups with mostly public Diseases
The ABO blood group system is identified in 1900. Its principle that antigens as sugars physically exposed on the exterior of red blood cells *RBCs* differ between individuals, who have immunological tolerance only toward what occurs in their own bodies.
Nagham Ghafel
doaj +1 more source
Transfusion management of patients with alloanti-Gerbich antibodies: Case report [PDF]
Introduction. Transfusion management of patients who are alloimmunized against high-prevalence erythrocyte antigens is often problematic. Strategy management depends, not only on the specific clinical circumstances of the patient, but also on the ...
Jovanović Radmila+3 more
doaj +1 more source
BACKGROUND: The clinical significance of anti-A1antibody among A2and A2B subgroups is controversial. Few case reports have shown clinically significant anti-A1antibody at 37°C, causing hemolysis of donor red cells.
Debasish Mishra+6 more
doaj +1 more source
Objectives: Red blood cell (RBC) immunization is a common complication in blood transfusion recipients. Patients with chronic kidney disease (CKD) eventually develop anemia, which is multifactorial, and requires regular blood transfusions, which exposes ...
Shafini Mohamed Yusoff+5 more
doaj +1 more source
The diagnosis of antibody-mediated rejection has become more common and represents a major cause of kidney graft loss. The ideal treatment remains unknown, with little evidence supporting the use of a specific therapy.
Rita M. Silva+7 more
doaj +1 more source