Results 171 to 180 of about 68,056 (282)

CO2 production predicted from isocitrate dehydrogenase activity and bisubstrate enzyme kinetics in the marine bacterium Pseudomonas nautica [PDF]

, 1996
Theodore T. Packard, Elisa Berdalet, D. Blasco, SO Roy, L St-Amand, B Lagacé, K Lee, JP Gagné   +7 more
openalex   +1 more source

Ivosidenib for IDH1‐Mutant Intrahepatic Cholangiocarcinoma: Insights From a Multicenter Real‐World Study

Liver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background & Aims Cholangiocarcinoma (CCA) is a rare cancer with limited therapeutic options and a poor prognosis. While first‐line combination therapies have improved outcomes, second‐line treatment remains challenging. Ivosidenib, an IDH1 inhibitor, has shown promise in treating IDH1 mutant CCA, but real‐world data is limited.
Monica Niger, Margherita Rimini, Florian Castet, Anna Melzer, Mario Domenico Rizzato, Tiziana Pressiani, Daniele Lavacchi, Giuseppe Aprile, Torsello Angela, Tiziana Saladino, Noventa Silvia, Pasqua Cito, Alessandro Pastorino, Eduardo Terán‐Brage, Carolina Sciortino, Silvia Camera, Chiara Pircher, Mara Persano, Vincenzo Mazzaferro, Silvia Foti, Kreina Sharela Vega, Thomas J. Ettrich, Lorenzo Antonuzzo, Lorenza Rimassa, Sara Lonardi, Lukas Perkhofer, Teresa Macarulla, Filippo Pietrantonio, Andrea Casadei‐Gardini   +28 more
wiley   +1 more source

A scoping review of proton radiation therapy and mutant-isocitrate dehydrogenase-inhibitors in IDH mutated lower-grade gliomas: pushing beyond surrogate end-points. [PDF]

Acta Neurochir (Wien)
Harba D, Corell A, Mansouri A, Brandal P, Blomstrand M, Jakola AS.   +5 more
europepmc   +1 more source

Cell death‐inducing DNA fragmentation factor alpha (DFFA)‐like effectors (CIDEs) improve lipid droplet (LD) formation and oil accumulation in plant tissues

Plant Biotechnology Journal, Volume 23, Issue 9, Page 3612-3627, September 2025.
Summary The cell death‐inducing DNA fragmentation factor alpha (DFFA)‐like effectors (CIDEs), including CIDEA, CIDEB and CIDEC, regulate the number and size of lipid droplets (LDs) in vertebrates. However, no homologue of CIDE has been reported in plants.
Yao Xiong, Caiyi Sun, Yuyan Xiang, Yuqing Li, Liang Guo, Shaoping Lu   +5 more
wiley   +1 more source

Correlation between Isocitrate Dehydrogenase Mutation and Immunohistochemical Expression of DNA Mismatch Repair Proteins in the Prognosis of Gliomas. [PDF]

Asian Pac J Cancer Prev
Saeed NM, Rashed H, Hussein S, Al-Karamany AS, Elmesallamy W, Waley AB, Obaya AA, Gharieb SA, Amgd K, Ibrahim SM, Abdelhamid MI, Khamis T, Mohamed AH.   +12 more
europepmc   +1 more source

A near‐gapless genome assembly of Pseudocydonia sinensis uncovers unique phenylpropanoid pathways

Plant Biotechnology Journal, Volume 23, Issue 9, Page 3581-3596, September 2025.
Summary Pseudocydonia sinensis, commonly known as Chinese quince, belongs to the Rosaceae family and is closely related to apple and pear. Despite its botanical significance, genomic resources for this species remain limited. We present a high‐quality, chromosome‐scale, and haplotype‐resolved genome assembly of P.
Yangxin Zhang, Shuangyu Zhang, Wenmeng Guo, Yuxin Zhang, Xiangxiang Chen, Qiaoming Yu, Yunxiao Liu, Yaqiang Sun, Ke Yu, Houhua Li, Fengwang Ma, Tao Zhao   +11 more
wiley   +1 more source

Isocitrate Dehydrogenase-Wildtype Glioma Adapts Toward Mutant Phenotypes and Enhanced Therapy Sensitivity Under D-2-Hydroxyglutarate Exposure. [PDF]

Biomedicines
Rocha G, Francés-Gómez C, Megías J, Muñoz-Hidalgo L, Casanova P, Haro-Estevez JF, Teruel-Martí V, Monleón D, San-Miguel T.   +8 more
europepmc   +1 more source

Yeast mitochondrial NAD⁺-dependent isocitrate dehydrogenase is an RNA-binding protein

, 1993
S.D.J. Elzinga, Amy L. Bednarz, K. van Oosterum, P. Dekker, Leslie Grivell   +4 more
openalex   +2 more sources

Identification of Enzymes Homologous to Isocitrate Dehydrogenase That Are Involved in Coenzyme B and Leucine Biosynthesis in Methanoarchaea [PDF]

, 2000
David M. Howell, Marion Graupner, Huimin Xu, Robert H. White   +3 more
openalex   +1 more source

Comparative Study of the Mitochondrial Proteome From Mesophyll, Vascular, and Guard Cells in Response to Carbon Starvation

Physiologia Plantarum, Volume 177, Issue 5, September/October 2025.
ABSTRACT A leaf is an organ composed of different tissues that fulfill specific functions. We hypothesized that since cells in vascular or mesophyll tissues as well as in stoma are developmentally tuned to operate their functions, mitochondria from these cells could exhibit significant metabolic differences.
Clément Boussardon, Shah Hussain, Olivier Keech   +2 more
wiley   +1 more source