Results 171 to 180 of about 344,376 (339)

MRI Radiomics for IDH Genotype Prediction in Glioblastoma Diagnosis [PDF]

open access: yesarXiv
Radiomics is a relatively new field which utilises automatically identified features from radiological scans. It has found a widespread application, particularly in oncology because many of the important oncological biomarkers are not visible to the naked eye.
arxiv  

Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria [PDF]

open access: yes, 2019
Methylmalonic acidemia (MMA) is a propionate pathway disorder caused by dysfunction of the mitochondrial enzyme methylmalonyl-CoA mutase (MMUT). MMUT catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA, an anaplerotic reaction which feeds into ...
Baumgartner, Matthias R   +6 more
core   +1 more source

Mechanism of reconstitution/activation of the soluble PQQ-dependent glucose dehydrogenase from Acinetobacter calcoaceticus: a comprehensive study [PDF]

open access: yesarXiv, 2019
The ability to switch on the activity of an enzyme through its spontaneous reconstitution has proven to be a valuable tool in fundamental studies of enzyme structure/reactivity relationships or in the design of artificial signal transduction systems in bioelectronics, synthetic biology, or bioanalytical applications.
arxiv  

Outcomes of Isocitrate Dehydrogenase Wild Type Glioblastoma after Re-irradiation

open access: yesClinical and Translational Radiation Oncology, 2023
Purpose: Glioblastomas (GBM) are the most common malignant primary brain tumors in adults and have a dismal prognosis. Patients frequently suffer from local tumor recurrences, with limited therapeutic options.
Felix Ehret   +8 more
doaj  

The Key Enzymes of Carbon Metabolism and the Glutathione Antioxidant System Protect Yarrowia lipolytica Yeast Against pH-Induced Stress

open access: yesJournal of Fungi
In this study, we first thoroughly assayed the response of the key enzymes of energy metabolism and the antioxidant system in Yarrowia lipolytica yeast at extreme pH.
Tatyana I. Rakhmanova   +5 more
doaj   +1 more source

A non‐redox role of the coenzyme in the catalysis of isocitrate dehydrogenase [PDF]

open access: bronze, 1976
Marie F. Carlier   +3 more
openalex   +1 more source

Language Models and Retrieval Augmented Generation for Automated Structured Data Extraction from Diagnostic Reports [PDF]

open access: yesarXiv
Purpose: To develop and evaluate an automated system for extracting structured clinical information from unstructured radiology and pathology reports using open-weights large language models (LMs) and retrieval augmented generation (RAG), and to assess the effects of model configuration variables on extraction performance.
arxiv  

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