Results 31 to 40 of about 347,846 (181)

Intermediary metabolism [PDF]

open access: yes, 2009
Caenorhabditis elegans has orthologs for most of the key enzymes involved in eukaryotic intermediary metabolism, suggesting that the major metabolic pathways are probably present in this species.
Braeckman, Bart   +2 more
core   +2 more sources

Frequency and prognostic significance of isocitrate dehydrogenase 1 mutations in cholangiocarcinoma: a systematic literature review.

open access: yesJournal of Gastrointestinal Oncology, 2019
Background The recognition of distinct molecular subgroups within cholangiocarcinoma (CC), along with the increasing availability of targeted therapies, suggests that further characterization of the prevalence and prognosis of frequently occurring ...
A. Boscoe, C. Rolland, R. Kelley
semanticscholar   +1 more source

Biochemical Characterization of Recombinant Isocitrate Dehydrogenase and Its Putative Role in the Physiology of an Acidophilic Micrarchaeon

open access: yesMicroorganisms, 2021
Despite several discoveries in recent years, the physiology of acidophilic Micrarchaeota, such as “Candidatus Micrarchaeum harzensis A_DKE”, remains largely enigmatic, as they highly express numerous genes encoding hypothetical proteins. Due to a lacking
Dennis Winkler   +2 more
doaj   +1 more source

LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]

open access: yes, 2014
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart   +7 more
core   +2 more sources

Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial Tumors

open access: yesIndian Journal of Neurosurgery, 2023
Introduction In consonance with current the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (2016), histological diagnosis of gliomas should be reinforced by molecular information.
Santosh Sharma   +5 more
doaj   +1 more source

Ventajas de la secuenciación de próxima generación sobre la hibridación fluorescente in situ para detectar la codeleción 1p/19q en oligodendrogliomas

open access: yesMedicina U.P.B., 2023
El perfil molecular de los gliomas permite garantizar la precisión del diagnóstico, informar el pronóstico e identificar opciones de tratamiento.
León Darío Ortiz   +4 more
doaj   +1 more source

Identification of Sequences Encoding Symbiodinium minutum Mitochondrial Proteins. [PDF]

open access: yes, 2016
The dinoflagellates are an extremely diverse group of algae closely related to the Apicomplexa and the ciliates. Much work has previously been undertaken to determine the presence of various biochemical pathways within dinoflagellate mitochondria ...
Butterfield, Erin R.   +2 more
core   +4 more sources

Isocitrate Dehydrogenase Mutations in Glioma: From Basic Discovery to Therapeutics Development

open access: yesFrontiers in Oncology, 2019
Isocitrate dehydrogenase (IDH) is a key rate-limiting enzyme in the Krebs cycle that plays an important role in energy metabolism. In recent years, it has been found that IDH mutations are closely related to the occurrence and development of glioma, and ...
Juan Huang   +5 more
semanticscholar   +1 more source

A histochemical study of the red and white muscle fibers Part III. Activity of the diphosphopyridine nucleotide diaphorase and triphosphopyridine nucleotide diaphorase in muscle fibers [PDF]

open access: yes, 1958
From the histochemical study of DPN and TPN diaphorase on the striated muscles of the cats, the following results were obtained. 1. M. gastrocnemius, which belongs to the white muscle by naked eye, consists of three types of muscle fibers distinguished ...
Ogata, Takuro
core   +1 more source

The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. [PDF]

open access: yesPLoS ONE, 2007
The tricarboxylic acid (TCA) cycle is an essential metabolic network in all oxidative organisms and provides precursors for anabolic processes and reducing factors (NADH and FADH(2)) that drive the generation of energy.
Ryan J Mailloux   +6 more
doaj   +1 more source

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