Results 31 to 40 of about 190,806 (273)
Purification of yeast isocitrate dehydrogenase [PDF]
Biochemical Journal, 1972 The NAD-linked isocitrate dehydrogenase from baker's yeast was purified to homogeneity (as judged by gel filtration and polyacrylamide-gel electrophoresis) with an overall yield of 50% by using dilute solutions of the allosteric effector (AMP) to elute the enzyme specifically from CM-cellulose.
openaire +2 more sources
Research Progress of Isocitrate Dehydrogenase Gene Mutation Therapy
Xiehe Yixue Zazhi, 2023 Isocitrate dehydrogenase (IDH), a key enzyme in the tricarboxylic acid cycle, plays an important role in cellular energy metabolism. When the IDH gene is mutated, the enzyme activity is altered, resulting in an accumulation of a large amount of the tumor
LIN Meijia +3 more
doaj +1 more source
The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. [PDF]
PLoS ONE, 2007 The tricarboxylic acid (TCA) cycle is an essential metabolic network in all oxidative organisms and provides precursors for anabolic processes and reducing factors (NADH and FADH(2)) that drive the generation of energy.
Ryan J Mailloux +6 more
doaj +1 more source
Prognostic value of Isocitrate Dehydrogenase And Mismatch Repair Genes In Gliomas [PDF]
Zagazig University Medical JournalBackground: Gliomas are considered the most prevalent malignancies of the central nervous system. These tumors are diffusely infiltrative and behave destructively toward the nearby brain tissue.
Dina Ahmed +4 more
doaj +1 more source
Indian Journal of Neurosurgery, 2023 Introduction In consonance with current the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (2016), histological diagnosis of gliomas should be reinforced by molecular information.
Santosh Sharma +5 more
doaj +1 more source
Microorganisms, 2021 Despite several discoveries in recent years, the physiology of acidophilic Micrarchaeota, such as “Candidatus Micrarchaeum harzensis A_DKE”, remains largely enigmatic, as they highly express numerous genes encoding hypothetical proteins. Due to a lacking
Dennis Winkler +2 more
doaj +1 more source
Isocitrate dehydrogenase from extremophiles; Molecular adaptations to high temperatures [PDF]
, 2006 Life on earth has adapted to a wide variety of environmental conditions, many of which are extreme to us humans. Temperature is one of the most important factors limiting biological activity and survival, but so far, biological activity has been observed
Stokke, Runar
core +1 more source
Structure and Function of Isocitrate Dehydrogenase From Escherichia coli ML308 [PDF]
, 1989 The level of activity of the NADP-dependent isocitrate dehydrogenase (ICDH) of E. coli ML308 is controlled by a reversible phosphorylation mechanism during growth on acetate as sole carbon source.
McKee, Jillian Stewart
core +6 more sources
Impact of IDH Mutations on DNA Methylation of Acute Myeloid Leukemia Related Genes: A Review Article
مجلة كلية الطبBackground: Acute myeloid leukemia is one of the deadliest hematologic malignancies that is marked by genetic alterations, abnormal cellular functions, and proliferation. Mutations in isocitrate dehydrogenase genes, particularly isocitrate dehydrogenase
Duha M. Bayram +2 more
doaj +1 more source
Medicina U.P.B., 2023 El perfil molecular de los gliomas permite garantizar la precisión del diagnóstico, informar el pronóstico e identificar opciones de tratamiento.
León Darío Ortiz +4 more
doaj +1 more source