Results 101 to 110 of about 294 (201)

SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2. [PDF]

Sci Rep, 2020
Smolková K, Špačková J, Gotvaldová K, Dvořák A, Křenková A, Hubálek M, Holendová B, Vítek L, Ježek P.   +8 more
europepmc   +1 more source

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

Head &Neck, Volume 48, Issue 10, Page 2810-2820, October 2026.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange, Mathilde Morisseau, Justin Michel, Thibaut Reverdy, Sylvain Morinière, Amaury Daste, Maxime Humbert, Caroline Viala, Pauline Corbaux, Tiffany Darbas, François‐Régis Ferrand, Valentin Favier, Camille Evrard, Diane Evrard, Delphine Farneti, Sarah Betrian‐Lagarde, Victor Sarradin   +16 more
wiley   +1 more source

Water Networks and Correlated Motions in Mutant Isocitrate Dehydrogenase 1 (IDH1) Are Critical for Allosteric Inhibitor Binding and Activity. [PDF]

Biochemistry, 2020
Chambers JM, Miller W, Quichocho G, Upadhye V, Matteo DA, Bobkov AA, Sohl CD, Schiffer JM.   +7 more
europepmc   +1 more source

Harnessing Natural Killer Cells: From Neuroimmunology to Novel Therapies for Central Nervous System Diseases

MedComm, Volume 7, Issue 10, October 2026.
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley   +1 more source

Endophytic Biostimulant Pyrroloquinoline Quinone Enhances Banana Growth and Primes Immunity Against Fusarium Wilt. [PDF]

Physiol Plant
Hung SW, Yu MY, Liu CH, Huang TC, Peng JH, Jang NY, Kuo CH, Yang YL, Ho YN, Chiang EI, Hwang HH, Huang CC.   +11 more
europepmc   +1 more source

Direct screening of enzyme activity using infrared matrix-assisted laser desorption electrospray ionization. [PDF]

Rapid Commun Mass Spectrom, 2017
Nazari M, Ekelöf M, Khodjaniyazova S, Elsen NL, Williams JD, Muddiman DC.   +5 more
europepmc   +1 more source

The heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism. [PDF]

Cell Death Dis, 2020
Ye S, Xu P, Huang M, Chen X, Zeng S, Wang Q, Chen J, Li K, Gao W, Liu R, Liu J, Shao Y, Zhang H, Xu Y, Zhang Q, Zhong Z, Wei Z, Wang J, Hao B, Huang W, Liu Q.   +20 more
europepmc   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

How do reducing equivalents increase insulin secretion? [PDF]

J Clin Invest, 2015
Attie AD.
europepmc   +1 more source

Feasibility of Spin‐ and Gradient‐Echo Dynamic Susceptibility Contrast MRI for Microvascular Characterization at 7 Tesla

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Spin‐ and‐gradient‐echo DSC MRI at 7 T allows for characterization of the microvasculature at an improved resolution and a reduced gadolinium‐based contrast agent dosage while maintaining increased vascular contrast. Ratios between normal‐appearing gray matter and white matter for relative cerebral blood volume and vessel size estimates were similar ...
Karen N. van der Werff, Daniëlle van Dorth, Krishnapriya Venugopal, Esther A. H. Warnert, Dirk H. J. Poot, Frans M. Vos, Marion Smits, Stefan Klein, C. Chad Quarles, Juan A. Hernandez‐Tamames, Johan A. F. Koekkoek, Jeroen de Bresser, Matthias J. P. van Osch   +12 more
wiley   +1 more source