Results 151 to 160 of about 67,105 (318)

Mixed‐mode membrane chromatography: mechanistic‐modeling‐based optimization and scale‐up of antibody charge variant separation using a novel membrane adsorber

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Efficient manufacturing of complex biopharmaceuticals increasingly relies on innovative downstream processing strategies. Membrane chromatography offers a promising alternative to resin‐based systems by enabling high‐throughput separations at elevated flow rates. Typically used in flow‐through mode, its industrial applications range
Jan Hedrich   +6 more
wiley   +1 more source

Mathematical model for steady state, simple ampholyte isoelectric focusing: Development, computer simulation and implementation [PDF]

open access: yes
The elimination of Ampholine from the system by establishing the pH gradient with simple ampholytes is proposed. A mathematical model was exercised at the level of the two-component system by using values for mobilities, diffusion coefficients, and ...
Allgyer, T. T., Palusinski, O. A.
core   +1 more source

Salivary gland alpha-amylases retain activity in wheat grains damaged by Eurygaster (Heteroptera: Scutelleridae) Sunn bugs

open access: yesВестник защиты растений
The Sunn pest Eurygaster integriceps and related wheat bugs (Sunn bugs) cause great damage to the wheat crop by injecting hydrolytic enzymes into the grain that liquefy the endosperm during extraintestinal digestion.
А. В. Конарев   +1 more
doaj   +1 more source

Development of a step‐gradient simulated moving bed process for the polishing of monoclonal antibodies with anion exchange chromatography

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND In recent years, biopharmaceutical applications in medicine have seen explosive growth and the need for efficient, rapid and inexpensive purification of these targets is the topic of tremendous research and development. The need to improve process efficiency has been an active area of investigation due to the tremendous potential ...
Yasmina MJ Harsy   +5 more
wiley   +1 more source

A comparison of an ATPase from the archaebacterium Halobacterium saccharovorum with the F1 moiety from the Escherichia coli ATP Synthase [PDF]

open access: yes
A purified ATPase associated with membranes from Halobacterium saccharovorum was compared with the F sub 1 moiety from the Escherichia coli ATP Synthase.
Hochstein, Lawrence I.   +1 more
core   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran   +5 more
wiley   +1 more source

Chewable Soft Gelatin Capsules: Design and Formulation Strategies for a Patient‐Preferred Dosage Alternative

open access: yesMacromolecular Materials and Engineering, EarlyView.
Chewable softgels are a patient‐preferred alternative to conventional oral forms, offering pleasant taste, fast onset, and suitability for children or patients with swallowing difficulties. However, they present relevant challenges in their formulation: the shell must balance chewability, machinability, and stability, while the fill must mask the ...
Almudena Naharros‐Molinero   +3 more
wiley   +1 more source

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