Results 91 to 100 of about 14,848 (191)

Echinococcus granulosus antigen B regulates T‐cell function through inhibition of signal transducer and activator of transcription 3 in experimental immune thrombocytopenia

open access: yesBritish Journal of Haematology, EarlyView.
During the pathological process of immune thrombocytopenia, signal transducer and activator of transcription 3 (STAT3) is activated by JAKs, leading to the production of a large number of inflammatory cytokines and promoting the activation of Th1, Th2 and Th17 cells.
Yingbin Yue   +4 more
wiley   +1 more source

Is Lutzomyia serrana (Diptera, Psychodidae, Phlebotominae) present in Ecuador ?

open access: yesParasite, 2004
We describe a multivariate metric comparison of three sandfly species showing strong differences in size, which questions the geographical distribution of one of them. Two species are represented by a single population (L. robusta and L.
Dujardin J.P., Le pont F., Maritnez E.
doaj   +1 more source

Developmental Changes in Lactate Dehydrogenase Isoenzyme Patterns of Rabbit Tissues. [PDF]

open access: bronze, 1968
Per Hellung‐Larsen   +5 more
openalex   +1 more source

Identification of new small molecules for selective inhibition of SERCA 1 in patient‐derived metastatic papillary thyroid cancer

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Papillary thyroid cancer (PTC) is a general thyroid cancer subtype; however, PTC is associated with metastasis or recurrence via anti‐cancer drug resistance, rendering it practically incurable. Therefore, effective and reliable clinical approaches are urgently required.
Seok‐Mo Kim   +5 more
wiley   +1 more source

Exosomal PKM2: A Noninvasive Diagnostic Marker Linking Macrophage Metabolic Reprogramming to Gastric Cancer Pathogenesis

open access: yesCancer Science, EarlyView.
Plasma exosomal PKM2 is a promising novel biomarker for early gastric cancer diagnosis. It activates the SREBP1‐mediated lipid synthesis pathway in macrophages, promoting their alternative activation and thereby driving tumor progression. ABSTRACT Tumor‐derived exosomes (TDEs) have emerged as vital biomarkers of multiple cancers.
Mengyun Yuan   +10 more
wiley   +1 more source

Enolases: Limitations for Implementation in Clinical Practice (Critical Review)

open access: yesОбщая реаниматология
Enolases (ENOs) are involved in glycolysis, which is critical for providing energy to cells under hypoxic conditions. ENOs are attracting the attention of researchers as a potential diagnostic marker for critical conditions.The aim of this review is to ...
A. М. Golubev
doaj  

Caracterización por isoenzimas de accesiones de Capsicum pertenecientes a la colección amazónica Colombiana

open access: yesRevista Colombiana de Biotecnología, 2005
Doscientas sesenta y una accesiones del género Capsicum del banco de germoplasma del Instituto Amazónico de Investigaciones Científicas (Sinchi) se evaluaron a través de cinco sistemas enzimáticos polimórficos: esterasa (EST), peroxidasa (PRX), 6 ...
Lorena Quintero Barrera   +3 more
doaj  

IMPDH2's Central Role in Cellular Growth and Diseases: A Potential Therapeutic Target

open access: yesCell Proliferation, EarlyView.
IMPDH2 is a rate‐limiting enzyme in guanine nucleotide biosynthesis. It plays diverse roles in various physiological and pathological processes: nucleotide metabolism, inflammation, immune function, ribosomal stress. Structural or regulatory alterations in IMPDH2 are linked to significant health issues, and critical relevance in disease progression. We
Zheng Li   +8 more
wiley   +1 more source

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