Results 91 to 100 of about 92,196 (294)

Sertraline and Phenytoin Drug Interaction in a Geriatric Patient [PDF]

open access: yes, 2017
This report presents the case of a 78-year-old man residing in a nursing home who presented with a 2-month history of increasing lethargy and confusion. These symptoms coincided with the initiation of sertraline in the patient.
Caprio, Thomas V.   +4 more
core   +2 more sources

Phylogenetic reconciliation provides new insights into the evolutionary diversification of the glutamine synthetase gene family in seed plants

open access: yesThe FEBS Journal, EarlyView.
Phylogenetic analyses of glutamine synthetase (GS) in seed plants revealed that all three major evolutionary lineages (GS2, GS1a, and GS1b) must have been present in the common ancestor, with GS2 being the first lineage to diverge. Unlike GS1b, GS1a and GS2 are usually single‐copy genes, even though they underwent duplications that resulted in ...
Elena Aledo   +3 more
wiley   +1 more source

Activation mechanism of pre-phenoloxidase in lobster and shrimp [PDF]

open access: yes, 1978
Phenoloxidase in shrimp and lobster is shown to exist in latent form which could be activated by trypsin and by an endogenous enzyme with tryptic activity.
Savagaon, K.A., Sreenivasan, A.
core  

Molecular genetics and pathophysiology of 17 beta-hydroxysteroid dehydrogenase 3 deficiency. [PDF]

open access: yes, 1996
Autosomal recessive mutations in the 17 beta-hydroxysteroid dehydrogenase 3 gene impair the formation of testosterone in the fetal testis and give rise to genetic males with female external genitalia.
Andersson, Stefan   +14 more
core   +1 more source

A new metabolic path in type 3 rickets

open access: yesThe FEBS Journal, EarlyView.
Rickets, a bone disorder, was historically categorised into either nutritional (vitamin D deficiency) or genetic forms involving loss‐of‐function mutations in mineral metabolism. Recently, a new mechanism, type 3 rickets, was discovered to be caused by a gain‐of‐function mutation in CYP3A4 (Ile301Thr).
Toshiya Senda, Yoshihisa Hirota
wiley   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges. [PDF]

open access: yesMed Res Rev
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Racca L, Baldanzi G, Massarotti A.
europepmc   +2 more sources

Creatine kinase in energy metabolic signaling in muscle [PDF]

open access: yes, 2007
There has been much debate on the mechanism of regulation of mitochondrial ATP synthesis to balance ATP consumption during changing cardiac workloads. A key role of creatine kinase (CK) isoenzymes in this regulation of oxidative phosphorylation and in ...
Johannes H. G. M. van Beek, Olav Kongas
core   +2 more sources

Cold hardiness mechanisms and modeling: existing approaches and future avenues

open access: yesNew Phytologist, EarlyView.
Summary Cold hardiness models are useful tools to predict cold damage in plants, such as those produced by unseasonal temperature cycles or by increased cold exposure. Although development of these models started about five decades ago, their applications remain limited.
Guillaume Charrier   +3 more
wiley   +1 more source

Structural and regulatory differences in amylase isoenzymes in germinating Brazilian barley cultivars

open access: yesGenetics and Molecular Biology, 2003
The amylase electrophoretic patterns of 10 Brazilian brewing-barley varieties with different malting grades and diastatic power were analyzed during the 7-day germination which occurs during the malting process.
Georg-Kraemer J.E., Cavalli S.S.
doaj  

Genetic structure and taxonomic position of Pinus uliginosa Neumann population from Wielkie Torfowisko Batorowskie in Stołowe Mts. (locus classicus)

open access: yesActa Societatis Botanicorum Poloniae, 2014
Genetic structure of Pinus uliginosa Neumann from Wielkie Tor-fowisko Batorowskie peat-bog (locus classicus) was studied by means of isoenzyme variability and compared with genetic structure of P. mugo Turra from Tatra Mts and P.
Anna Siedlewska, Wiesław Prus-Głowacki
doaj   +1 more source

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