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The Dual-Function C2H2-Type Zinc-Finger Transcription Factor GmZFP7 Contributes to Isoflavone Accumulation in Soybean.

New Phytologist, 2022
Isoflavones are a class of secondary metabolites produced by legumes and play important roles in human health and plant stress tolerance. The C2H2 zinc-finger transcription factor functions in plant stress tolerance, but little is known about its ...
Yue Feng   +12 more
semanticscholar   +1 more source

Anti-Inflammatory and Antiproliferative Prenylated Isoflavone Derivatives from the Fruits of Ficus carica.

Journal of Agricultural and Food Chemistry, 2019
Ficus carica is an Asian species of flowering plant belonging to the genus Ficus of the family Moraceae, native to Western Asia and the Middle East. Its fruits, usually known as common fig or fig, have been consumed as a very popular health-promoting ...
Yan-Ping Liu   +6 more
semanticscholar   +1 more source

Isoflavone biochanin A, a novel nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element activator, protects against oxidative damage in HepG2 cells.

Biofactors, 2019
Isoflavones are one group of the major flavonoids and possess multiple biological activities due to their antioxidant properties. However, a clear antioxidant mechanism of dietary isoflavones is still remained to be answered.
Fuqiang Liang   +6 more
semanticscholar   +1 more source

Isoflavones and cardiovascular disease

Maturitas, 2010
The specific profile of estrogens on cardiovascular risk, with limiting action on atherogenesis but a less clear protection on cardiovascular episodes, might be improved by other agonists of the estrogen receptor, such as isoflavones. By using a systematic search based on the electronic Medline database plus a hand-search of reference lists of selected
Antonio, Cano   +2 more
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Synthesis of isoflavones

Journal of Heterocyclic Chemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Medical value of isoflavones

Journal of Chinese Integrative Medicine, 2003
Isoflavones as a kind of phytoestrogen exist in soy plant widely. With the advantages of estrogen, they can regulate endocrine function of the human body, reduce blood cholesterol, decrease the incidence of coronary heart disease, prevent osteoporosis, inhibit tumor growth, and relieve pain.
Ning, Du, Yong, Xu
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Bioavailability of isoflavones

Journal of Chromatography B, 2002
Isoflavones are disease protective components of soybeans. Isoflavone metabolism and bioavailability are key to understanding their biological effects. Isoflavone glucuronides, dominant biotransformation products in humans that are more hydrophilic than isoflavone aglycones, activate human natural killer cells in vitro but are less toxic to NK cells ...
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Isoflavones Promote Mitochondrial Biogenesis

The Journal of Pharmacology and Experimental Therapeutics, 2008
Mitochondrial damage is often both the cause and outcome of cell injury resulting from a variety of toxic insults, hypoxia, or trauma. Increasing mitochondrial biogenesis after renal proximal tubular cell (RPTC) injury accelerated the recovery of mitochondrial and cellular functions (Biochem Biophys Res Commun 355:734-739, 2007).
Kyle A, Rasbach, Rick G, Schnellmann
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Enzymic synthesis of isoflavones

European Journal of Biochemistry, 1986
The NADPH and oxygen‐dependent conversion of (2S)‐naringenin to genistein catalyzed by a microsomal preparation from elicitor‐treated soybean cell suspension cultures has been resolved into two steps. In the first step (2S)‐naringenin is converted to a product (P‐2) which yields genistein in a second step.
G, Kochs, H, Grisebach
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