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Isoflavones: Anti-Inflammatory Benefit and Possible Caveats

open access: yesNutrients, 2016
Inflammation, a biological response of body tissues to harmful stimuli, is also known to be involved in a host of diseases, such as obesity, atherosclerosis, rheumatoid arthritis, and even cancer.
Bing Yu, Daiwen Chen, Chen Daiwen
exaly   +2 more sources
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Bioavailability of isoflavones

Journal of Chromatography B, 2002
Isoflavones are disease protective components of soybeans. Isoflavone metabolism and bioavailability are key to understanding their biological effects. Isoflavone glucuronides, dominant biotransformation products in humans that are more hydrophilic than isoflavone aglycones, activate human natural killer cells in vitro but are less toxic to NK cells ...
openaire   +2 more sources

Synthesis of isoflavones

Journal of Heterocyclic Chemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Isoflavones and cardiovascular disease

Maturitas, 2010
The specific profile of estrogens on cardiovascular risk, with limiting action on atherogenesis but a less clear protection on cardiovascular episodes, might be improved by other agonists of the estrogen receptor, such as isoflavones. By using a systematic search based on the electronic Medline database plus a hand-search of reference lists of selected
Antonio, Cano   +2 more
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Isoflavones for hypercholesterolaemia in adults

Cochrane Database of Systematic Reviews, 2013
Hypercholesterolaemia is a significant risk factor for cardiovascular diseases. Isoflavones may be effective in improving hypercholesterolaemia.To assess the effects of isoflavones for hypercholesterolaemia.We searched the following databases: The Cochrane Library (Issue 9, 2012), MEDLINE, EMBASE, Chinese BioMedical Database and China National ...
Yu, Qin   +8 more
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Medical value of isoflavones

Journal of Chinese Integrative Medicine, 2003
Isoflavones as a kind of phytoestrogen exist in soy plant widely. With the advantages of estrogen, they can regulate endocrine function of the human body, reduce blood cholesterol, decrease the incidence of coronary heart disease, prevent osteoporosis, inhibit tumor growth, and relieve pain.
Ning, Du, Yong, Xu
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Enzymic synthesis of isoflavones

European Journal of Biochemistry, 1986
The NADPH and oxygen‐dependent conversion of (2S)‐naringenin to genistein catalyzed by a microsomal preparation from elicitor‐treated soybean cell suspension cultures has been resolved into two steps. In the first step (2S)‐naringenin is converted to a product (P‐2) which yields genistein in a second step.
G, Kochs, H, Grisebach
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Stereospecific microbial production of isoflavanones from isoflavones and isoflavone glucosides

Applied Microbiology and Biotechnology, 2011
A Gram-negative anaerobic microorganism, MRG-1, isolated from human intestine showed high activities of deglycosylation and reduction of daidzin, based on rapid TLC analysis. A rod-shaped strain MRG-1 was identified as a new species showing 91.0% homology to Coprobacillus species, based on 16S rRNA sequence analysis.
Hye-Yeon, Park   +2 more
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Chemistry of heteroanalogs of isoflavones 14. Isoxazole analogs of isoflavones

Chemistry of Heterocyclic Compounds, 1993
Isoxazole analogs of isoflavones have been synthesized by the cyclization of α-(3-isoxazolyl)-2-hydroxyacetophenones. Their alkylation, acylation, and electrophilic substitution reactions, and reactions with binucleophiles have been studied. 3-(3-Isoxazolyl)-7-methoxychromones are rearranged selectively into 2-aminochromone derivatives by the action of
N. V. Gorbulenko   +2 more
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Soy Isoflavones: a Safety Review

Nutrition Reviews, 2003
Soy isoflavones have been a component of the diet of certain populations for centuries. The consumption of soy generally has been considered beneficial, with a potentially protective effect against a number of chronic diseases; because of their estrogenic activity, however, negative effects of isoflavones have been postulated.
Munro, IC   +6 more
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