Results 51 to 60 of about 801 (163)

Flavonoids and Phenolic Compounds From the Parasitic Gymnosperm Endemic to New Caledonia

open access: yesNatural Product Communications, 2022
Parasitaxus usta (Podocarpaceae) is the only parasitic gymnosperm and endemic to New Caledonia. In this survey, 11 flavonoids and 6 phenolic compounds were isolated from the aerial parts.
Tsukasa Iwashina   +4 more
doaj   +1 more source

Polyphenolic promiscuity, inflammation-coupled selectivity: Whether PAINs filters mask an antiviral asset

open access: yesFrontiers in Pharmacology, 2022
The Covid-19 pandemic has elicited much laboratory and clinical research attention on vaccines, mAbs, and certain small-molecule antivirals against SARS-CoV-2 infection.
Rick Sheridan   +2 more
doaj   +1 more source

Review: Pharmacological effects of Capparis spinosa L. [PDF]

open access: yes, 2016
Medicinal plants have been known as one of the most important therapeutic agents since ancient times. During the last two decades, much attention has been paid to the health-promoting effects of edible medicinal plants, because of multiple beneficial ...
Abraham   +114 more
core   +1 more source

Regulating divergent transcriptomes through mrna splicing and its modulation using various small compounds [PDF]

open access: yes, 2020
Human transcriptomes are more divergent than genes and contribute to the sophistication of life. This divergence is derived from various isoforms arising from alternative splicing.
Fujita, Ken Ichi   +4 more
core   +1 more source

Exploring the Antitumor Mechanisms of Zingiberis Rhizoma Combined with Coptidis Rhizoma Using a Network Pharmacology Approach

open access: yesBioMed Research International, Volume 2020, Issue 1, 2020., 2020
Background. Although the combination of Zingiberis rhizoma (ZR) and Coptidis rhizoma (CR) is a classic traditional Chinese medicine‐based herbal pair used for its antitumor effect, the material basis and underlying mechanisms are unclear. Here, a network pharmacology approach was used to elucidate the antitumor mechanisms of ZR‐CR.
Meng Wang   +3 more
wiley   +1 more source

Long and repeat-rich intronic sequences favor circular RNA formation under conditions of reduced spliceosome activity [PDF]

open access: yes, 2019
Circular RNAs (circRNAs), an important class of regulatory RNAs, have been shown to be the most prevalent in the brain compared with other tissues. However the processes governing their biogenesis in neurons are still elusive.
Chen, W.   +4 more
core   +1 more source

Splicing to Keep Cycling:The Importance of Pre-mRNA Splicing during the Cell Cycle [PDF]

open access: yes, 2021
Pre-mRNA splicing is a fundamental process in mammalian gene expression, and alternative splicing plays an extensive role in generating protein diversity.
Ajuh   +146 more
core   +2 more sources

Preparation, evaluation and metabolites study in rats of novel Isoginkgetin-loaded TPGS/soluplus mixed nanomicelles

open access: yesJournal of Food and Drug Analysis, 2020
At present, cancer is one of the most lethal diseases in the world, and researchers are committed to developing effective anticancer drugs. Isoginkgetin (IGG) is a kind of biflavone with the potential to treat cancer due to the features of altering the cell cycle and inhibiting tumor cell infiltration.
Feng, Xue   +5 more
openaire   +3 more sources

Human Telomerase RNA Processing and Quality Control

open access: yesCell Reports, 2015
The non-coding RNA subunit of telomerase provides the template for telomerase activity. In diverse fungi, 3′ end processing of telomerase RNA involves a single cleavage by the spliceosome.
Chi-Kang Tseng   +5 more
doaj   +1 more source

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