Results 21 to 30 of about 4,732 (200)

Isoliquiritigenin (ISL) inhibits ErbB3 signaling in prostate cancer cells

BioFactors, 2006
AbstractIsoliquiritigenin (ISL), a flavonoid found in licorice, shallot, and bean sprouts, has been identified as a potent anti‐tumor promoting agent. We previously demonstrated that ISL reduces cell proliferation and induces apoptosis in DU145 human prostate cancer cells and MAT‐LyLu (MLL) rat prostate cancer cells.
Jae In, Jung, Eunkyung, Chung, Mi Ra, Seon, Hyun-Kyung, Shin, Eun Ji, Kim, Soon Sung, Lim, Won-Yoon, Chung, Kwang-Kyun, Park, Jung Han Yoon, Park   +8 more
openaire   +4 more sources

Isoliquiritigenin Modulates the Effect of LINC01503 
on Lung Squamous Carcinoma Cells

Chinese Journal of Lung Cancer
Background and objective Isoliquiritigenin (ISL) is an important pharmacological constituent of Glycyrrhiza glabra, which possesses a range of physiological and pharmacological activities, as well as significant antitumor activity, and can be used as a ...
Mengshi ZHANG, Yishuang CUI, Yihan YAO, Yanlei GE, Junqing GAN, Ye JIN, Guogui SUN   +6 more
doaj   +3 more sources

Therapeutic properties of isoliquiritigenin with molecular modeling studies: investigation of anti-pancreatic acinar cell tumor and HMG-CoA reductase inhibitor activity for treatment of hypercholesterolemia

Archives of Medical Science, 2022
Introduction Isoliquiritigenin, one of the components in the root of Glycyrrhiza glabra L., is a member of the flavonoids, which are known to have anti-tumor activity in vitro and in vivo.
Jihua Li, Fengfeng Zhu, Weiguo Xu, Ping Che   +3 more
doaj   +1 more source

Isoliquiritigenin induced hepatotoxicity and endoplasmic reticulum stress in zebrafish embryos

Scientific Reports
Isoliquiritigenin (ISL), a naturally occurring flavonoid derived from licorice root, exhibits antioxidant, anticancer, anti-inflammatory, and anti-allergic properties, and is frequently detected in both environmental and human samples. Previous studies from our lab have demonstrated that ISL exposure can lead to developmental deformities and aberrant ...
Deliang Hu, Yuqing Yang, Lei Fang, Shijie Fan, Ling Lin, Puying Luo, Yuanhuan Xiong, Yufang Su   +7 more
openaire   +4 more sources

ISOLYQUIRITIGENIN AFFECTS PHAGOCYTES FUNCTIONS AND INCREASES MICE SURVIVAL RATE IN STAPHYLOCOCCAL INFECTION

Фармация и фармакология (Пятигорск), 2021
The results of studying the effect of isoliquiritigenin on animal survival in the model of staphylococcal infection and the function of human and animal phagocytes are presented in this article.The aim of the investigation was to study the effect of an ...
E. A. Solenova, S. I. Pavlova
doaj   +1 more source

ANTIBACTERIAL AND IMMUNOTROPIC PROPERTIES OF ISOLIQUIRITIGENIN IN GENERALIZED STAPHYLOCOCCAL INFECTION IN MICE

Фармация и фармакология (Пятигорск), 2020
The article is devoted to the study of the effects of isoliquiritigenin in generalized bacterial infections.The aim is to study antibacterial and immunotropic mechanisms and effects of isoliquiritigenin in generalized staphylococcal infections in a mouse
E. A. Solyonova, S. I. Pavlova
doaj   +1 more source

The inhibitory effect of isoliquiritigenin on human platelets in vitro

Annals of Translational Medicine, 2023
Platelets play important roles in several physiological and pathological processes. Multiple antiplatelet drugs have been developed for clinical practice. The active components of traditional Chinese medicine with antithrombotic effects are promising drugs to modulate platelet function.
Wu, Yingying, Deng, Cheng, Wang, Yixuan, Ming, Zhangyin, Mei, Heng, Hu, Yu   +5 more
openaire   +2 more sources

Isoliquiritigenin, an active ingredient of Glycyrrhiza, elicits antinociceptive effects via inhibition of Nav channels [PDF]

, 2021
九州歯科大学博士（歯学）Glycyrrhiza extract has been used for the treatment of oral and gastric ulcers, but the analgesic mechanism remains unknown. In the present study, we investigated the effects of isoliquiritigenin, an active ingredient of Glycyrrhiza, on Nav ...
Ujihara Izumi, Hitomi Suzuro, Kokabu Shoichiro, Miyamura Yuichi, Omiya Yuji, Ono Kentaro, Morimoto Yasuhiro   +6 more
core   +1 more source

Correction: Targeting digestive system cancers with isoliquiritigenin: a comprehensive review of antitumor mechanisms [PDF]

Frontiers in Pharmacology
Zhichun Li, Ruohan Feng, Jinze Li, Jinglu Bai, Nuo Li, Zhenhua Cui, Zhenhua Cui, Xiaobin Zhang   +7 more
doaj   +2 more sources

MS/MS spectrum and cleavage pathway of Isoliquiritigenin.

, 2023
MS/MS spectrum and cleavage pathway of Isoliquiritigenin.
Mengxin Yang (10684155), Yiran Jin (15864387), Yingfeng Du (16806833), Dedong Zhang (12033156), Juan Gao (228368), Weiwei Xie (419745), Zhiqing Zhang (507600), Xuqing Wen (16806830)   +7 more
core   +1 more source