Results 111 to 120 of about 12,847 (298)
Crystallographic proof for an extended hydrogen-bonding network in small prolyl isomerases
, 2011 Parvulins compose a family of small peptidyl-prolyl isomerases (PPIases) involved in protein folding and protein quality control. A number of amino acids in the catalytic cavity are highly conserved, but their precise role within the catalytic mechanism ...
Lukas Hoppstock +13 more
core +1 more source
, 2020 BackgroundFlavonoids have been characterized as a prominent class of compounds to treat thrombotic diseases through the inhibition of thiol isomerases. Syzygium cumini is a flavonoid-rich medicinal plant that contains myricetin and gallic acid. Little is
Vinicyus Teles Chagas (8384052) +9 more
core +1 more source
International Journal of Cancer, EarlyView.Plasmid‐like DNA sequences frequently found in bovine milk and serum have been proposed as infectious agents promoting indirect carcinogenesis. This multi‐omics study detected immune cells positive for these bovine meat and milk factors (BMMFs) in patients with lung cancer, with BMMF expression inversely correlated with smoking intensity.
Nives Cecere +17 more
wiley +1 more source
, 2020 BackgroundFlavonoids have been characterized as a prominent class of compounds to treat thrombotic diseases through the inhibition of thiol isomerases. Syzygium cumini is a flavonoid-rich medicinal plant that contains myricetin and gallic acid. Little is
Vinicyus Teles Chagas (8384052) +9 more
core +1 more source
Interdisciplinary Medicine, EarlyView.Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong +15 more
wiley +1 more source
Prolyl Isomerases Show Low Sequence Specificity toward the Residue Following the Proline
, 2016 Prolyl isomerases catalyze the cis/trans isomerization of peptide bonds preceding proline. Previously, we had determined the specificity toward the residue before the proline for cyclophilin-, FKBP-, and parvulin-type prolyl isomerases by using proline ...
Franz X. Schmid (1748071) +3 more
core +1 more source
, 2020 BackgroundFlavonoids have been characterized as a prominent class of compounds to treat thrombotic diseases through the inhibition of thiol isomerases. Syzygium cumini is a flavonoid-rich medicinal plant that contains myricetin and gallic acid. Little is
Vinicyus Teles Chagas (8384052) +9 more
core +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
Interdisciplinary Medicine, EarlyView.This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Structure/Function Relationships of Sucrose Isomerases with Different Product Specificity
, 2010 Proceedings of the Symposium on Amylases and Related Enzymes, 2009International audienceSucrose isomerases from Protaminobacter rubrum, SmuA, and from Pseudomonas mesoacidophila MX-45, MutB, have been crystallized, and their three-dimensional structures ...
Richard Haser +8 more
core +1 more source
, 2020 BackgroundFlavonoids have been characterized as a prominent class of compounds to treat thrombotic diseases through the inhibition of thiol isomerases. Syzygium cumini is a flavonoid-rich medicinal plant that contains myricetin and gallic acid. Little is
Vinicyus Teles Chagas (8384052) +9 more
core +1 more source