Identification of a genetic marker for isometamidium chloride resistance in Trypanosoma congolense
International Journal for Parasitology, 2005 Isometamidium chloride has remained a very important prophylactic and therapeutic drug against trypanosomosis in cattle since its introduction into the market in the 1950s with, unfortunately, a concomitant development of resistance in trypanosomosis endemic areas. Amplified Fragment Length Polymorphism (AFLP) was used to compare two isogenic clones of
Delespaux, V. +3 more
openaire +3 more sources
Atypical human infections by animal trypanosomes: evaluation of human and animal trypanocidal drugs against Trypanosoma lewisi in Wistar rats [PDF]
, 2016 Trypanosomosis is a disease of medical and veterinary importance, mainly distributed in tropical areas of Africa, Latin America and Asia. Some Trypanosoma species are typically pathogenic for animals, such as Trypanosoma vivax, T. congolense, T.
Chalermwong, Piangjai +4 more
core
Immunology and Cell Biology of Parasitic Diseases
, 2010 BioMed Research International, Volume 2010, Issue 1, 2010.
Luis I. Terrazas +2 more
wiley +1 more source
Mise en évidence d'une résistance aux trypanocides parmi des souches de Trypanosoma congolense récemment isolées au Burkina [PDF]
, 1984 Dix-huit souches de T. congolense ont fait l'objet d'une épreuve de sensibilité à l'acétate de diminazène et à l'isométamidium chez la souris. L'intérêt et les limites de cette épreuve sont discutés. Les 13 souches de T.
Authié, Edith
core
African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]
, 2017 African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar +160 more
core +1 more source
Trypanosoma (Duttonella) vivax: Its biology, epidemiology, pathogenesis, and introduction in the New World - a review [PDF]
, 2008 The biology, epidemiology, pathogenesis, diagnostic techniques, and history of the introduction of Trypanosoma (Duttonella) vivax in the New World are reviewed.
Desquesnes, Marc +5 more
core
Trypanosoma evansi e trypanosoma vivax: biologia, diagnóstico e controle. [PDF]
, 2017 Tripanosomoses; Taxonomia; Morfologia; Ciclo vital; Teminologia utiilzada para os tripanosomas baseada no Trypanosoma brucei; Manutenção dos Tripanosomas; Variação molecular em Tripanosomas; Ecologia e sociologia da variação antigênica; Genética de ...
RAMIREZ, L. +3 more
core
Heliyon, 2018 The current study was undertaken from December 2015 to May 2016 with the aim of determining and comparing the pathogenicity and response to diminazene aceturate (DA) and isometamidium chloride (ISM) treatment in experimentally infected mice with ...
Muluken Yayeh +7 more
doaj +1 more source
Time-dose response of Trypanosoma congolense bloodstream forms to diminazene and isometamidium
Veterinary Parasitology, 1994 Trypanosoma congolense bloodstream forms were propagated in vitro axenically in a simplified cultivation medium at 34 degrees C. Viability of a drug-sensitive and a drug-resistant clone were examined for 10 days following exposure to 0.1, 1.0 and 10.0 micrograms ml-1 of diminazene aceturate and 0.1, 1.0 and 10.0 ng ml-1 of isometamidium chloride for ...
Kaminsky, R., Chuma, F., Wasike, R.P.N.
openaire +3 more sources
The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing [PDF]
, 2018 Kinetoplastid parasites—trypanosomes and leishmanias—infect millions of humans and cause economically devastating diseases of livestock, and the few existing drugs have serious deficiencies.
Barrett, Michael P. +11 more
core +3 more sources