Results 61 to 70 of about 527 (157)

Chemoprophylaxis: Boran cattle can be productive under high tsetse challenge

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1984
La productivité du bétail Boran maintenu avec chimioprophylaxie sous risque trypanosomien élevé a été évaluée au Ranch de Mkwaja en Tanzanie. Vingt mille relevés de vêlage enregistrés sur une période de 10 ans ont été analysés.
J.C.M. Trail, M. Murray, Keith Sones, J.M.C. Jibbo, J. Durkin, D. Light   +5 more
doaj   +1 more source

Spatiotemporal changes in prevalence of Sodalis glossinidius, Spiroplasma spp. and trypanosome species in wild Glossina tachinoides from Sora‐Mboum animal African trypanosomiasis focus in northern Cameroon

Insect Science, Volume 32, Issue 5, Page 1713-1725, October 2025.
Abstract Sterile Insect Technique (SIT) has proven effective to reduce tsetse population density in large infected areas where animal African trypanosomosis (AAT) and human African trypanosomiasis (HAT) elimination was difficult to achieve. However, the decrease in mass production of insectary‐reared tsetse and the limited but incomplete knowledge on ...
Steve Feudjio Soffack, Tito T. Melachio Tanekou, Hugues C. Nana Djeunga, Oumarou Farikou, Ginette I. Kame Ngasse, Mureille C. Tchami Mbagnia, Murielle Wondji, Charles S. Wondji, Hager Khalil, Adly M. M. Abd‐Alla, Anne Geiger, Gustave Simo, Flobert Njiokou   +12 more
wiley   +1 more source

Reduced accumulation of isometamidium by drug-resistant Trypanosoma congolense

Parasitology, 1991
The accumulation of the trypanocide isometamidium chloride (Samorin®, RMB Animal Health Ltd, UK) by a range of clones of Trypanosoma congolense with varying sensitivity to the drug, was measured by methods based on the fluorescence of isometamidium. Fluorescence microscopy and flow cytometry showed a reduction in drug accumulation by resistant clones ...
Sutherland, I.A., Peregrine, A.S., Lonsdale-Eccles, J.D., Holmes, P.H.   +3 more
openaire   +3 more sources

Cross-resistance associated with development of resistance to isometamidium in a clone of Trypanosoma congolense [PDF]

Antimicrobial Agents and Chemotherapy, 1997
Resistance to isometamidium was increased 94-fold in a clone of Trypanosoma congolense (clone IL 1180) by repeated subcurative treatment of infected mice for 11 months. This was associated with 3.4-, 33-, and 4.2-fold increases in resistance to diminazene, homidium, and quinapyramine, respectively. Both T.
Peregrine, A.S., Gray, M.A., Moloo, S.K.
openaire   +2 more sources

Investigation of Novel Isatinylhydantoin Derivatives as Potential Anti‐Kinetoplastid Agents

ChemMedChem, Volume 20, Issue 1, January 2, 2025.
A series of isatinylhydantoin derivatives were synthesized and investigated for antileishmanial and antitrypanosomal activities in vitro and in vivo. The derivative 5 was identified with higher leishmanicidal activity than the clinical drug amphotericin B while 4b was uncovered as in vitro trypanocidal hit against T. congolense parasite.
Keamogetswe Sechoaro, Janine Aucamp, Christina Kannigadu, Helena D. Janse van Rensburg, Keisuke Suganuma, David D. N'Da   +5 more
wiley   +1 more source

Characterization and phylogenetic analysis of multidrug-resistant protein-encoding genes in Trypanosoma evansi isolated from buffaloes in Ngawi district, Indonesia [PDF]

Veterinary World, 2019
Background and Aim: Excessive use of trypanocidal drugs can lead to cases of drug resistance. Multiple cases of resistance have been widely reported for drugs such as isometamidium chloride and diminazene aceturate. These cases deserve serious attention,
Mohammad Mirza Nuryady, Rini Widayanti, Raden Wisnu Nurcahyo, Brilyantika Fadjrinatha, Ahmad Fahrurrozi Z. S.   +4 more
doaj   +1 more source

Observation d'une flambée de trypanosomose équine due à Trypanosoma vivax en zone urbaine au Sénégal [PDF]

Tropicultura, 1996
Observation of an Outbreak of Equine Trypanosomiasis due to Trypanosoma vivax in Urban Environment in Senegal. An outbreak of trypanosomiasis in imported and local horses and ponies occurred in September 1994 in a private horseriding farm near Dakar ...
Dehoux, JP., Diaw, M., Buldgen, A.
doaj  

Tractable Quinolone Hydrazides Exhibiting Sub‐Micromolar and Broad Spectrum Antitrypanosomal Activities

ChemMedChem, Volume 19, Issue 9, May 2, 2024.
Several (sub)species of Trypanosoma are responsible for human African trypanosomiasis (HAT), Chagas disease, and Nagana. These (sub)species have different drug susceptibility profiles. This work reports several easily accessed quinolone hydrazides exhibiting sub‐micromolar activities against multiple (sub)species of Trypanosoma.
Kgothatso A. Chirwa, Karol R. Francisco, Phelelisiwe S. Dube, Hayoung Park, Lesetja J. Legoabe, Thaiz Rodrigues Teixeira, Conor R. Caffrey, Richard M. Beteck   +7 more
wiley   +1 more source

Seroprevalencia de tripanosomosis bovina determinada por ELISAi posterior al tratamiento profiláctico con isometamidium en un hato del municipio Muñoz del estado Apure, Venezuela

Revista Científica, 2012
  La tripanosomosis bovina genera anualmente cuantiosas pérdidas económicas en la producción ganadera del país. Algunas explotaciones de tipo extensivo han establecido planes anuales de control de estos hemoparásitos, los cuales consisten en la ...
Ariadna Rangel Rivas, Francia Reyes, Alfredo Mijares   +2 more
doaj  

Mise en évidence d'une résistance aux trypanocides parmi des souches de Trypanosoma congolense récemment isolées au Burkina

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1984
Dix-huit souches de T. congolense ont fait l'objet d'une épreuve de sensibilité à l'acétate de diminazène et à l'isométamidium chez la souris. L'intérêt et les limites de cette épreuve sont discutés. Les 13 souches de T.
Edith Authié
doaj   +1 more source