Results 41 to 50 of about 484 (116)
An overview is presented of the results obtained with biodegradable sustained release devices (SRDs) containing a mixture of polymers and either isometamidium (ISMM) or ethidium. Under controlled laboratory conditions (monthly challenge with tsetse flies
S Geerts, JRA Brandt, R De Deken
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The occurrence of cross-resistance among melarsoprol-resistant Trypanosoma brucei rhodesiense isolates was investigated in this study. The isolates, T. b. rhodesiense KETRI 237, 2538, 1992, 2709, 2694 and 3530, had been obtained from sleeping sickness
N. Maina, J.M. Kagira
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Drug Resistant Trypanosomes: a Threat to Cattle Production in the Southwest of Ethiopia
Trypanosomosis is an important disease of cattle in the southwest of Ethiopia. At present chemotherapy and chemoprophylaxis are the only practical methods available for the control of animal trypanosomosis, but their effectiveness is being eroded by the ...
H. Chaka, G. Abébé
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Trypanosoma congolense is a protozoan parasite that is transmitted by tsetse flies, causing African Animal Trypanosomiasis, also known as Nagana, in sub-Saharan Africa. Nagana is a fatal disease of livestock that causes severe economic losses.
M. Gysin +5 more
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Resistance to trypanocidal drugs has been detected in various African countries and is a serious impediment to the control of livestock trypanosomosis.
S. Jamal +6 more
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Trypanosoma vivax infections cause nonspecific clinical signs in cattle associated with aparasitemic intervals, making disease diagnosis a challenge.
Kayo José Garcia de Almeida Castilho Neto +7 more
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The protective efficacy of isometamidium chloride (ISMM) and diminazene aceturate (DIM) against Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population was assessed in southeast Uganda.
J.W. Magona +3 more
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Aberrant use and poor quality of trypanocides: a risk for drug resistance in south western Ethiopia
Background Trypanocidal drugs have been used to control African animal trypanosomosis for several decades. In Ethiopia, these drugs are available from both authorized (legal) and unauthorized (illegal) sources but documentation on utilization practices ...
T. Tekle +14 more
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The effect of treatment time on the efficacy of trypanocides in rats experimentally infected with Trypanosoma brucei brucei was assessed. The thirty albino rats utilized in this study were divided into six groups, each with five rats.
Ikenna O. EZEH +7 more
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Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracyclines and enrofloxacin. [PDF]
BACKGROUND: Because of the development of resistance in trypanosomes to trypanocidal drugs, the livelihood of millions of livestock keepers in sub-Saharan Africa is threatened now more than ever.
Vincent Delespaux +7 more
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