Laboratory and Field Evaluation of Biodegradable Polyesters for Sustained Release of Isometamidium and Ethidium [PDF]
Memorias do Instituto Oswaldo Cruz, 1999 An overview is presented of the results obtained with biodegradable sustained release devices (SRDs) containing a mixture of polymers and either isometamidium (ISMM) or ethidium. Under controlled laboratory conditions (monthly challenge with tsetse flies
S Geerts, JRA Brandt, R De Deken
doaj +4 more sources
Indian Journal of Animal SciencesThe monomorphic, non-cyclic, extracellular haemoprotozoan parasite, Trypanosoma evansi leads to Surra disease in domesticated animals. Currently, diminazene aceturate (DA) and isometamidium chloride (ISM) are the most used chemotherapeutic agents for ...
SNEHIL GUPTA +6 more
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High prevalence of Trypanosoma spp. and apparent trypanocidal drugs inefficacy in cattle in Al Radom National Park, Sudan [PDF]
Scientific ReportsTrypanosomosis is a major infectious disease affecting cattle in Sudan. In South Darfur, data on cattle trypanosomosis has been limited since the Darfur civil war (2003–2007). This study assessed the prevalence and distribution of Trypanosoma spp.
Khalid M. Mohammedsalih +9 more
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Identification of a genetic marker for isometamidium chloride resistance in Trypanosoma congolense
International Journal for Parasitology, 2005 Isometamidium chloride has remained a very important prophylactic and therapeutic drug against trypanosomosis in cattle since its introduction into the market in the 1950s with, unfortunately, a concomitant development of resistance in trypanosomosis endemic areas. Amplified Fragment Length Polymorphism (AFLP) was used to compare two isogenic clones of
V Delespaux +2 more
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The economic cost of bovine trypanosomosis in pastoral and ago pastoral communities surrounding Murchision Falls National park, Buliisa district, Uganda [PDF]
BMC Veterinary Research, 2022 Background: Animal diseases that are endemic like tsetse transmitted trypanosomosis cause the continuous expenditure of financial resources of livestock farmers and loss of productivity of livestock.
Daniel Kizza +8 more
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Systematic Review and Meta-Analysis on Knowledge Attitude and Practices on African Animal Trypanocide Resistance [PDF]
Tropical Medicine and Infectious Disease, 2022 Background: African trypanocide resistance is an emerging public health emergency whose control requires a revisit on farmer’s knowledge, attitudes, and practices in developing countries.
Keneth Iceland Kasozi +5 more
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STUDIES ON ISOMETAMIDIUM: THE EFFECT OF ISOMETAMIDIUM, HOMIDIUM AND PYRITHIDIUM ON THE INFECTIVITY OF TRYPANOSOMAS FOR MICE [PDF]
British Journal of Pharmacology and Chemotherapy, 1965 J. HILL
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Managing African animal trypanosomiasis in Benin: Knowledge, attitudes, and practices of cattle owners in the West Atacora zone [PDF]
Veterinary WorldBackground and Aim: African animal trypanosomiasis (AAT), transmitted by tsetse flies, severely constrains livestock productivity in sub-Saharan Africa.
Yao Akpo +3 more
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Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracyclines and enrofloxacin. [PDF]
PLoS Neglected Tropical Diseases, 2010 BACKGROUND: Because of the development of resistance in trypanosomes to trypanocidal drugs, the livelihood of millions of livestock keepers in sub-Saharan Africa is threatened now more than ever.
Vincent Delespaux +7 more
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Trypanocide Use and Molecular Characterization of Trypanosomes Resistant to Diminazene Aceturate in Cattle in Northern Côte D’Ivoire [PDF]
Tropical Medicine and Infectious DiseaseThe resistance of trypanosomes to the doses of trypanocide administered by farmers to their animals acts as a real brake on efforts to control to combat African trypanosomiasis.
Jean-Yves Ekra +6 more
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