Haematological indices in Trypanosoma brucei brucei (Federe isolate) infected Nigerian donkeys (Equus asinus) treated with homidium and isometamidium chloride of ciprofloxacin in broiler chickens after single intravenous and intraingluvial administration [PDF]
The efficacy of intramuscular administration of Homidium chloride (Novidium®) and Isometamidium chloride (Sécuridium®) in Nigerian donkeys (Equus asinus) experimentally infected with T. b. brucei (Federe isolate) was investigated.
Queen Nneka Oparah +4 more
doaj +3 more sources
Trypanosoma evansi and Surra: A review and perspectives on transmission, epidemiology and control, impact, and zoonotic aspects [PDF]
This paper reviews the transmission modes of Trypanosoma evansi. Its worldwide distribution is attributed to mechanical transmission. While the role of tabanids is clear, we raise questions on the relative role of Haematobia sp.
Dargantes, Alan +5 more
core +4 more sources
Drug quality analysis of isometamidium chloride hydrochloride and diminazene diaceturate used for the treatment of African animal trypanosomosis in West Africa [PDF]
Background Diminazene diaceturate (DA) and isometamidium chloride hydrochloride (ISM) are with homidium bromide, the main molecules used to treat African Animal Trypanosomosis (AAT).
Zakaria Bengaly +11 more
doaj +2 more sources
Determination of Residual Isometamidium in Cattle Tissues and Milk by HPLC
A determination method for the antitripanosomal agent, isometamidium (IMD) in cattle muscle, liver, fat and milk has been developed by using HPLC. The drug was extracted from a sample with acetonitrile-0.25mol/L ammonium formate methanol solution, and purified by liquid-liquid partition with ethyl acetate and water, followed by extraction of the water ...
Kazunari Kondo +4 more
openalex +3 more sources
Longitudinal observational (single cohort) study on the causes of trypanocide failure in cases of African animal trypanosomosis in cattle near wildlife protected areas of Northern Tanzania. [PDF]
African animal trypanosomosis (AAT) in cattle is primarily managed through trypanocide administration and insecticide application. Trypanocides can be used for both treatment and prophylaxis, but failure is often reported; this may occur due to ...
Shauna Richards +13 more
doaj +2 more sources
The relationship between serum concentrations of the prophylactic trypanocidal drug isometamidium chloride and protection against tsetse challenge with two populations of Trypanosoma congolense was investigated in Boran (Bos indicus) cattle, using an isometamidium-ELISA.
M C Eisler, S K Moloo, P H Holmes
exaly +4 more sources
Prothidium and isometamidium as drug against Trypanosoma brucei canine trypanosomiasis
Le Prothidium et l'Isométamidium ont été utilisés dans le traitement de plusieurs cas de trypanosomiase expérimentale du chien à Trypanosoma brucei. Le Prothidium est administré à raison de 2 mg/kg de la solution à 2 p.100 et l'Isométamidium 1 mg/kg de ...
Saydil Touré
doaj +3 more sources
Equine trypanosomiasis, a systematic review: Disease management. [PDF]
Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To answer the study question: In equines what are the effects of disease management of trypanosomiasis on disease severity (individual level) and disease prevalence (population level) compared to no intervention? Study Design Systematic review.
Raftery AG +5 more
europepmc +2 more sources
INFLUENCE OF NUTRITION ON TRYPANOSOME ISOMETAMIDIUM CHLORIDE CHEMOPROPHYLAXIS
Thirty six weaner wistar rats were used to study the effect of protein nutrition on trypanosome isometamidium chloride prophylaxis. Two groups of rats A and B (n = 18 per group) were maintained on 21% and 14.5% crude protein diet respectively for the twenty eight days.
P.A. Nnadi, P.A. Onyeyili
openalex +2 more sources
Assessment of Veterinary Drug Availability, Storage Conditions, and Handling Practices in and Around Nekemte Town, Southwestern Oromia, Ethiopia. [PDF]
Animal diseases pose a significant threat to both animal welfare and productivity, making veterinary drugs essential for their prevention, treatment, and control. In developing countries including Ethiopia, several challenges such as limited drug availability, inadequate storage facilities, improper handling, and insufficient knowledge among veterinary
Mekonen AW +4 more
europepmc +2 more sources

